Late and Long-Term Side Effects - BMT Infonet
Bronchiolitis obliterans syndrome (BOS), also called graft-versus-host disease (GVHD) of the lungs, occurs in approximately 5% of patients who were transplanted with donor cells …
Current approaches to prevent and treat GVHD after allogeneic stem …
2018年11月30日 · Graft-versus-host disease (GVHD) remains a challenge after allogeneic hematopoietic cell transplantation (HCT). GVHD occurs when immunocompetent donor T cells …
Acute Graft-versus-Host-Disease (GVHD) Symptoms and Treatment
Recognizing acute GVHD is crucial. Understand how it affects different organs in the body, explore prevention methods, and review common treatment options.
Introduction to Graft-versus-Host Disease (GVHD) | BMT Infonet
2022年4月30日 · Graft-versus-Host-Disease (GVHD) occurs when transplanted donor cells attack the patient’s body. It can affect virtually every organ in the body and may require prolonged …
Chronic Graft-Versus-Host Disease - The EBMT Handbook - NCBI …
2024年4月11日 · Chronic GVHD (cGVHD) is the most relevant cause of late non-relapse morbidity and subsequent mortality (approximately 25%) following allo-HCT (Grube et al. 2016).
Post-Transplantation Cyclophosphamide-Based Graft-versus-Host …
2023年6月21日 · In patients undergoing allogeneic hematopoietic stem-cell transplantation (HSCT), a calcineurin inhibitor plus methotrexate has been a standard prophylaxis against …
BMT CTN Technical Document Acute & Chronic GVHD Guidance 1. Acute Graft-Vs-Host Disease (GVHD) 1.1. Introduction The Acute GVHD Technical Committee has reviewed and …
Prophylaxis and management of graft versus host disease after ... - EBMT
2020年3月25日 · To standardize GVHD management, the EBMT gives recommendations that apply to the setting of HLA-identical sibling or unrelated donor transplantation of adult patients …
Randomized Phase III BMT CTN Trial of Calcineurin Inhibitor–Free ...
2021年12月2日 · This randomized phase III trial compared three approaches for chronic GVHD prevention and specifically investigated whether two CNI-free approaches, ex vivo TCD using …
A New Standard in Graft-versus-Host Disease Prophylaxis? An ...
2020年12月1日 · BMT CTN 1703 builds on recent randomized studies showing encouraging results with the use of PTCy-based GVHD prophylaxis in related and unrelated allogeneic RIC …