2025年3月30日 · GRIA1 (Glutamate Ionotropic Receptor AMPA Type Subunit 1) is a Protein Coding gene. Diseases associated with GRIA1 include Intellectual Developmental Disorder, Autosomal Dominant 67 and Intellectual Developmental Disorder, Autosomal Recessive 76.

2021年11月15日 · Gria1 encodes the GluA1 (also known as GluR-A or GluR1) subunit of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) subtype of glutamate receptors. GluA1-containing AMPA receptors...

Identification and functional evaluation of GRIA1 missense and truncation variants in individuals with ID: An emerging neurodevelopmental syndrome. MicroRNA miR-18a-3p promotes osteoporosis and possibly contributes to spinal fracture by inhibiting the glutamate AMPA receptor subunit 1 gene (GRIA1).

Ionotropic glutamate receptor that functions as a ligand-gated cation channel, gated by L-glutamate and glutamatergic ag onists such as alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), quisqualic acid, and kainic acid 1, 2, 3, 4, 5. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

2022年3月14日 · Prior evidence suggests that hypofunction of AMPA-type glutamate receptors (AMPARs) containing the subunit GLUA1, encoded by GRIA1, might be causally related to impairments of selective...

GRIA1 encodes the GluA1 subunit of α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors, which are ligand-gated ion channels that act as excitatory receptors for the neurotransmitter L -glutamate (Glu).

The GRIA1 gene encodes a subunit of ionotropic glutamate AMPA receptors, which are ligand-gated cation channels that mediate the majority of excitatory synaptic transmission in the central nervous system and play a role in synaptic plasticity mechanisms thought to underlie learning and memory (summary by Ismail et al., 2022).

2024年2月4日 · Clinical resource with information about GRIA1, A genome-wide association study of aging., Biological insights from 108 schizophrenia-associated genetic loci., Genetic variations in GRIA1 on chromosome 5q33 related to asparaginase hypersensitivity., Genome-wide association analysis identifies 13 new risk loci for schizophrenia., Genome-wide ...

Previous symbol(s) and name(s): GLUR1, glutamate receptor, ionotropic, AMPA 1 Type: gene with protein product

2022年7月7日 · GRIA1 encodes the GluA1 subunit of α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors, which are ligand-gated ion channels that act as excitatory receptors for the neurotransmitter L-glutamate (Glu).