Co-occurrence panel for gene symbol: GON-2. Gene target information for GON-2. Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

We have characterized the properties of five loss-of-function alleles of a newly described gene, which we call gon-2. In gon-2 mutants, gonadogenesis is severely impaired; in some animals, …

2015年11月25日 · The C. elegans genes, gon-2, gtl-1 and gtl-2, encode paralogous TRP cation channel proteins that are similar in sequence and function to human TRPM6 and TRPM7. We …

1997年11月1日 · We have characterized the properties of five loss-of-function alleles of a newly described gene, which we call gon-2. In gon-2 mutants, gonadogenesis is severely impaired; …

2001年3月21日 · Mutant alleles of gon-2 affect evolutionarily conserved amino acid residues. Northern analyses suggest that gon-2 expression is not limited to gonadal tissues. 1. …

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2001年3月21日 · The C. elegans gon-2 gene is required for the post-embryonic mitotic cell divisions of the gonadal precursor cells. A single major transcript of approximately 6.7 kb is …

2015年11月25日 · The genome of the nematode, Caenorhabitis elegans, contains three paralogous genes, gon-2, gtl-1 and gtl-2, which encode cation channel proteins (GON-2, GTL …

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Inactivation of gem-1 enhances the gonadogenesis defects of gon-2 hypomorphic mutations, suggesting that these two genes probably act in parallel to promote gonadal cell divisions.