Glutathione S-transferase - Wikipedia
Glutathione S-transferases (GSTs), previously known as ligandins, are a family of eukaryotic and prokaryotic phase II metabolic isozymes best known for their ability to catalyze the conjugation of the reduced form of glutathione (GSH) to xenobiotic substrates for the purpose of detoxification.
Glutathione S-Transferase - an overview | ScienceDirect Topics
The glutathione S-transferases (GSTs) or GSH transferases are the multi-gene family of enzymes that catalyse the conjugation of reduced GSH to a variety of electrophilic substances; and function like house-keepers to detoxify the xenobiotic substances in cells (Eaton and Bammler, 1999).
Glutathione transferases: substrates, inihibitors and pro-drugs …
2018年1月24日 · Laliberte, R. E. et al. Glutathione s-transferase omega 1-1 is a target of cytokine release inhibitory drugs and may be responsible for their effect on interleukin-1beta posttranslational...
Glutathione-Related Enzymes and Proteins: A Review - PMC
Involvement of γ-glutamyl transpeptidase (GGT), glutathione-S-transferases (GST), their subfamily of Membrane Associated Proteins in Eicosanoid and Glutathione metabolism (MAPEG), and glyoxylases (Glo) in the intracellular metabolism of GSH.
Glutathione S-transferase: a versatile protein family - PubMed
Glutathione-S transferase (GST) is a most ancient protein superfamily of multipurpose roles and evolved principally from gene duplication of an ancestral GSH binding protein.
Glutathione transferases as mediators of signaling pathways
2010年7月2日 · Glutathione transferases (EC 2.5.1.18), also referred to as glutathione S-transferases or GSTs, are members of a multigene family of isoenzymes ubiquitously expressed in most living organisms....
Glutathione S-transferase: a versatile protein family | 3 Biotech
Glutathione-S transferase (GST) is a most ancient protein superfamily of multipurpose roles and evolved principally from gene duplication of an ancestral GSH binding protein.
Glutathione S-transferase: A versatile and dynamic enzyme
2024年11月19日 · The dynamic and versatile group of enzymes referred to as glutathione S-transferases (GSTs) play diverse roles in cellular detoxification, safeguarding hosts from oxidative damage, and performing various other functions.
The glutathione S-transferase Gstt1 drives survival and …
2024年6月11日 · GSTT1 encodes the glutathione S-transferase (GST) theta 1 enzyme, a member of a superfamily of proteins that catalyse the conjugation of reduced glutathione (GSH) to a variety of...
Structure, function and evolution of glutathione transferases ...
2001年11月15日 · The glutathione transferases (GSTs; also known as glutathione S-transferases) are major phase II detoxification enzymes found mainly in the cytosol. In addition to their role in catalysing the conjugation of electrophilic substrates to glutathione (GSH), these enzymes also carry out a range of other …
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