2025年2月15日 · Structural damage to gill tissues resulted in the downregulation of ECM–receptor interaction and focal adhesion pathways, which inactivated gill cells and thus reduced the …

2024年1月30日 · Increased mucus, hemocyte infiltration, and lifting of the lamellar epithelium suggested that gill epithelium was suffering damage under ammonia-N stress. Meanwhile, the …

2022年1月30日 · Comparing with the gonad, the gill showed strong immune-related responses towards bacteria challenge, with abundant immune-related signaling pathway being disturbed, …

Tissue inhibitors of metalloproteinases (TIMPs), which inhibit matrix metalloproteinases (MMPs) as well as the closely related, a disintegrin and metalloproteinases (ADAMs) and ADAMs with …

2024年8月1日 · At the molecular biological level, we found that the macroscopic changes of interlamellar cell mass during gill remodeling were correlated with the changes of extracellular …

2023年1月30日 · In this study, gill morphological and transcriptomic profiles of spotted sea bass was characterized after alkalinity stress. Several morphological parameters of gill tissues were …

细胞外基质 (ECM)是由细胞分泌到细胞外间质中的大分子物质所构成的复杂网架动态结构，由间质基质和 基底膜 构成，占机体质量的三分之一以上。 间质基质主要由细胞分泌产生，是一种 …

2017年8月30日 · Fibrosis is a common driver of end-stage organ failure in most organs. It is characterised by excessive accumulation of extracellular matrix (ECM) proteins.

2017年10月15日 · Activated fibroblasts are considered major drivers of fibrotic disease progression through the production of excessive extracellular matrix (ECM) in response to …

Regulated turnover of extracellular matrix (ECM) is an important component of tissue homeostasis. In recent years, the enzymes that participate in, and control ECM turnover have …