1997年8月19日 · The absolute reduction in mortality and number of lives saved per 1000 patients treated with GIK was 4.9% and 49 lives (95% CI, 14 to 83), respectively (Table 3). High-dose intravenous GIK therapy has been advocated by Rogers et al 12 to achieve adequate suppression of plasma FFA levels.

2020年3月10日 · GIK therapy significantly reduced the incidence of low cardiac output syndrome and congestive heart failure. GIK also decreased the incidence of new‐onset AF and nonsustained supraventricular tachycardia but not ventricular fibrillation.

Glucose-insulin-potassium (GIK) infusion has been shown to have favourable cardiac effects by different mechanisms (1 – 4). Some of these benefits include a reduced infarct size, an enhanced functional recovery and a 28% decreased rate of mortality in …

2008年5月13日 · GIK was given as an infusion of 80 mmol of KCl in 500 mL of 20% glucose at a rate of 3 mL per kilogram of body weight per hour over an 8- to 12-hour period and a continuous infusion of short-acting insulin (50 U of Actrapid HM, Novo Nordisk) in 50 mL of …

The unified GIK regimen was more effective than the diverse GIK regimen for glycaemic control and did not increase the number of patients developing hypoglycaemia. This validated written GIK regimen can be safely used in a general surgical department.

Glucose-insulin-potassium (GIK) infusion has a beneficial role in myocardial protection and is associated with better post-operative outcomes without increasing the risk of non-cardiac complications. Keywords: Coronary artery bypass grafting, Glucose-insulin-potassium (GIK) solution, Myocardial protection.

High-dose GIK solution had no adverse effects on the hemodynamics in AMI patients treated with primary PCI. It can improve cardiac function by lowering SVRI. In the 6-month follow-up, it improved cardiac remodeling. Keywords: Acute myocardial infarction, glucose–insulin–potassium, reperfusion therapy.

The infusion of glucose-insulin-potassium (GIK) has yielded conflicting results in terms of cardioprotective effects. We conducted a meta-analysis to examine the impact of perioperative GIK infusion in early outcome after cardiac surgery.

2014年11月25日 · Glucose–insulin–potassium (GIK) has long been advocated as an adjunctive treatment for patients with cardiac dysfunction during episodes of ischemia and reperfusion. Experimental and clinical studies have demonstrated that GIK could improve the efficiency of energy use, reduce circulating free fatty acids, and be anti-apoptotic [1, 2]. GIK ...

2007年11月28日 · Intervention: High-dose GIK solution consisting of 25% glucose, 50 U/L of regular insulin, and 80 mEq/L of potassium infused at 1.5 mL/kg per hour for 24 hours. Main outcome measures: Mortality rates at 30 days and 6 months in the OASIS-6 GIK trial and rates of death, heart failure, and the composite of death or heart failure at 3 and 30 days ...