Translate is a tool which allows the translation of a nucleotide (DNA/RNA) sequence to a protein sequence.

Translate. Home; Programmatic Access; Contact; Translate - Programmatic access Parameters dna_sequence Bare nucleotide sequence output_format The output format.

Compute pI/Mw for UniProtKB entries or one user-entered sequence Please enter one or several UniProtKB AC/ID (e.g. P04406 or ALBU_HUMAN), each on a separate line.Alternatively, enter one protein sequence in single letter code.

UniProtKB/Swiss-Prot is the manually annotated and reviewed section of the UniProt Knowledgebase (UniProtKB). It is a high quality annotated and non-redundant protein sequence database, which brings together experimental results, …

Eukaryotic translation initiation factor 2-alpha kinase 3 Gene: EIF2AK3 Feedback?

PeptideMass [Documentation / References] cleaves a protein sequence from the UniProt Knowledgebase (Swiss-Prot and TrEMBL) or a user-entered protein sequence with a chosen enzyme, and computes the masses of the generated peptides. The tool also returns theoretical isoelectric point and mass values for the protein of interest

ProtParam [Documentation / Reference] is a tool which allows the computation of various physical and chemical parameters for a given protein stored in UniProtKB or for a user entered protein sequence. The computed parameters include the molecular weight, theoretical pI, amino acid composition, atomic composition, extinction coefficient, estimated half-life, instability index, …

Sequence information Variant position: 281 The position of the amino-acid change on the UniProtKB canonical protein sequence. Protein sequence length: 281 The length of the canonical sequence. Location on the sequence: SSSLGAFFAGDLPPPLQAGA A The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, …

Variant information Variant position: 126 The position of the amino-acid change on the UniProtKB canonical protein sequence. Type of variant: US The variants are classified into three categories: LP/P, LB/B and US. LP/P: likely pathogenic or pathogenic. LB/B: likely benign or benign. US: uncertain significance; Residue change: From Isoleucine (I) to Valine (V) at position 126 …

This tool calculates the estimated pI and Mw of a specified Swiss-Prot/TrEMBL entry or a user-entered AA sequence. These parameters are useful if you want to know the approximate region of a 2-D gel where a protein may be found.