Nucleotide-binding oligomerization domain-containing protein 2 (NOD2), also known as caspase recruitment domain-containing protein 15 (CARD15) or inflammatory bowel disease protein 1 …

The NOD2 gene (previously known as CARD15) provides instructions for making a protein that plays an important role in immune system function. The NOD2 protein is active in some types …

2025年3月30日 · NOD2 (Nucleotide Binding Oligomerization Domain Containing 2) is a Protein Coding gene. Diseases associated with NOD2 include Blau Syndrome and Inflammatory …

2024年5月14日 · Gene mutations of NOD2 lead to the development of autoimmune diseases such as Crohn’s disease and Blau syndrome. Recently, NOD2 has been shown to be …

Gene ID: 64127, updated on 8-Feb-2025. This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats …

In this review, we discuss recent developments about the pathway and mechanisms of regulation of NOD2 and illustrate the principal functions of the gene, with particular emphasis on its …

Nucleotide-binding oligomerization domain 2 (NOD2) is an intracellular pattern recognition receptor that senses bacterial peptidoglycan (PGN)-conserved motifs in cytosol and stimulates …

2023年12月20日 · The nod2 gene encodes a protein called Nod2 which plays a crucial role in the antibacterial defense mechanism of the human body. This gene is a member of the nucleotide …

HGNC Approved Gene Symbol: NOD2. Cytogenetic location: 16q12.1 Genomic coordinates (GRCh38) : 16:50,693,606-50,733,075 (from NCBI) Inflammatory responses are triggered …

NOD2 is an intracellular pattern recognition receptor (PRR) responsible for the recognition of pathogens as well as the activation of many biochemical processes within cells of the host …