Glycogen synthase kinase-3 beta - Wikipedia
Glycogen synthase kinase-3 beta, (GSK-3 beta), is an enzyme that in humans is encoded by the GSK3B gene. [5] [6] In mice, the enzyme is encoded by the Gsk3b gene. [7] Abnormal …
GSK-3β - 百度百科
进一步机制研究发现，二甲双胍/低血糖组合的协同抗肿瘤作用由PP2A下游的糖原合成酶激酶3β（GSK3β）活化介导，导致肿瘤细胞中促存活蛋白MCL-1的表达降低和细胞死亡。 PP2A …
GSK3B Gene - GeneCards | GSK3B Protein | GSK3B Antibody
Dec 25, 2024 · GSK3B (Glycogen Synthase Kinase 3 Beta) is a Protein Coding gene. Diseases associated with GSK3B include Cardiomyopathy, Familial Hypertrophic, 1 and Hematologic …
糖原合酶激酶3 (GSK-3)概述 - 知乎 - 知乎专栏
GSK-3β2是大脑中表达的GSK-3β的选择性剪接变体。 GSK-3β已经与各种配体结晶。 它的总体形状为所有激酶所共有，包括一个主要由β折叠组成的小的N末端叶和一个主要由α螺旋组成的大 …
Glycogen synthase kinase-3 (GSK3): regulation, actions, and …
Nov 27, 2021 · Glycogen synthase kinase-3 (GSK3) may be the busiest kinase in most cells, with over 100 known substrates to deal with. How does GSK3 maintain control to selectively …
糖原合酶激酶 3 β（GSK3B）基因 | MCE - MCE-生物活性分子 ...
它是葡萄糖稳态的负调节剂，参与能量代谢、炎症、内质网应激、线粒体功能障碍和细胞凋亡途径。 该基因的缺陷与帕金森病和阿尔茨海默病有关。 [RefSeq 提供，2017 年 8 月] The protein …
In vivo regulation of glycogen synthase kinase 3β activity in …
Aug 17, 2017 · Glycogen synthase kinase 3β (GSK3β) is a multifunctional protein kinase that targets Ser/Thr residues with a priming phosphorylation at the fourth amino acid on the...
New insights into the role of GSK-3β in the brain: from ...
GSK-3β is essential for the control of glucose metabolism, signal transduction, and tissue homeostasis. As more than 100 known proteins have been identified as GSK-3β substrates, it …
Glycogen Synthase Kinase 3 (GSK3): Its Role and Inhibitors
Glycogen Synthase Kinase 3 (GSK3) is one of the Serine/Threonine protein kinases, which has gained a lot of attention for its role in a variety of pathways. It has two isoforms, GSK3α and …
GSK-3β在相关疾病中的作用及致病机制的研究进展
糖原合成酶激酶-3 (GSK-3)是一种存在于所有真核细胞质中的丝氨酸/苏氨酸蛋白激酶,分为α和β两种亚型。 研究显示GSK-3β在调控糖代谢,细胞炎症反应,神经及心脏功能和生殖功能中具有重 …