2018年5月9日 · The purpose of this study was to examine the role of CAA, operationally-defined as the presence of cerebral microbleeds on GRE MRI, in the context of autosomal dominant AD and in the relationship we observed previously between …

Topographical distribution of white matter hyperintensities (WMH) are hypothesized to vary by cerebrovascular risk factors. We used an unbiased pattern discovery approach to identify distinct WMH spatial patterns and investigate their association ...

White matter hyperintensities (WMH) have been extensively associated with cognitive impairment and reductions in gray matter volume (GMv) independently. This study explored whether WMH lesion volume mediates the relationship between cerebral patterns of GMv and cognition in 521 (mean age 57.7 years) cognitively unimpaired middle‐aged individuals.

Grey matter (GM) alterations may contribute to cognitive decline in individuals with white matter hyperintensities (WMH) but no consensus has yet emerged. Here, we investigated cortical thickness and grey matter volume in 23 WMH patients with mild cognitive impairment (WMH-MCI), 43 WMH patients without cognitive impairment, and 55 healthy controls.

Small subcortical infarcts (SSI) frequently coexist with brain white matter hyperintensity (WMH) lesions. We sought to determine whether preexisting WMH burden relates to SSI volume, SSI etiology, and 90-day functional outcome.

2024年11月30日 · White matter hyperintensities (WMH) disrupt structural network efficiency. Structural efficiency loss from WMH relates to cognitive dysfunction in aging. Limited evidence links WMH to late-onset epilepsy. MRI has considerably increased our pathophysiological knowledge of age-related brain abnormalities.

2017年3月12日 · GRE：梯度回波 (Gradient echo)。 传统的T1、T2都是用的自旋回波（spin echo）序列，应用GRE序列后有个T2*弛豫，以此为加权的成像叫T2*加权成像。 这个T2*就是证明核磁在出血领域实力的急先锋。 当然各个厂家还是够得瑟的，瞧这五花八门的名字（这不明摆着给我们临床医生添乱吗？ ），来个表展示一下[6]： 表1 T2*加权成像名称一览表. （点击可查看高清大图） 那么，脑出血在T2*上是什么样子呢？ 下图分别是超急性期，急性期，亚急性早期，亚 …

2024年11月11日 · The histopathological correlates of both posterior confluent WMHs and WMH multispots were indicative of white matter rarefaction and chronic neuroinflammation, although less apparent in WMH multispots.

2018年11月20日 · WMH involve changes in the periventricular, deep and subcortical white matter, visualized as patchy or diffuse areas of hypodensities on plain computed tomography (CT) or hyperintensities on T2 – weighted magnetic resonance imaging (MRI).

2006年7月7日 · WMH are seen on the baseline (left) and follow-up (right) MRI FLAIR sequences in a 75 year woman with a history of remote left temporal hemorrhage and multiple asymptomatic lobar microbleeds. The results of WMH segmentation (green-colored regions-of-interest) are shown in the bottom panels.