2025年3月30日 · GNA11 (G Protein Subunit Alpha 11) is a Protein Coding gene. Diseases associated with GNA11 include Hypocalciuric Hypercalcemia, Familial, Type Ii and …

Guanine nucleotide-binding protein subunit alpha-11 is a protein that in humans is encoded by the GNA11 gene. [5] [6] Together with GNAQ (its paralogue), it functions as a Gq alpha subunit. [7]

GNA11 is involved in signalling of gonadotropin-releasing hormone receptor, which negatively regulates cell growth. Down-regulation is suggested to be involved in human breast cancers. …

The GNA11 gene provides instructions for making one component, the alpha (α) subunit, of a protein complex called a guanine nucleotide-binding protein (G protein). Learn about this gene …

GNAQ and GNA11 genes encode protein members of the q class of G-protein alpha subunits involved in mediating signals between G-protein coupled receptors (GPCRs) and downstream …

gnaq 和 gna11 基因在几乎 80-90% 的葡萄膜黑色素瘤中以相互排斥的模式发生突变。这些基因编码异源三聚体 g 蛋白、gq 和 g11 的 α 亚基；因此，这些基因的突变会导致几个重要信号通路 …

2018年10月15日 · In the current sample, the genes GNAS, GNAQ, and GNA11 were widely altered across cancer types, and these alterations often were accompanied by specific …

2021年9月22日 · Mouse Gna11 and Gna15 (139314) are tandemly duplicated in a head-to-tail array. Davignon et al. (1996) showed that the upstream gene, Gna11, is ubiquitously …

该基因编码其中一个 alpha 亚基 (亚基 alpha-11) 。 该基因的突变与低尿钙性高钙血症 II 型 (HHC2) 和低钙血症显性 2 (HYPOC2) 相关。 HHC2 和 HYPOC2 患者分别表现出对细胞外钙浓度变化 …

2024年1月7日 · Clinical resource with information about GNA11, Autosomal dominant hypocalcemia 2, Familial hypocalciuric hypercalcemia 2, and available tests. There are links to …