2020年1月1日 · Dysfunction of the GH/insulin-like growth factor 1 (IGF-1)/ghrelin axis was linked to hyperalgesia and several common clinical pain syndromes. Low levels of GH and IGF-1 were linked to pain hypersensitivity, whereas ghrelin appeared to provide analgesic effects.

2019年1月5日 · This review aims to examine the potential molecular mechanisms through which GH-related signaling modulates sensory hypersensitivity in rodents, the clinical pharmacology of GH, and the clinical evidence of GH treatment for several common pain syndromes.

Growth hormone (GH) increases lean body mass, reduces fat mass, increases exercise tolerance and maximum oxygen uptake, enhances muscle strength, and improves linear growth. Long-term studies of GH administration offer conflicting results regarding its safety, which has led to strict FDA criteria for GH use.

2015年3月8日 · GHS is an acronym for the Globally Harmonized System of Classification and Labeling of Chemicals, a framework that standardizes the classification and labeling of chemicals worldwide. Its goal is to establish criteria for the classification of health, physical and environmental hazards, and specify what information should be included on hazard ...

2019年2月22日 · The QLQ-C30 includes an overall GHS/QoL domain, five functional domains (physical, emotional, cognitive, social, and role functioning), and nine symptom domains (fatigue, nausea/vomiting, pain...

Results: GHS was present in 52 patients (48.6%) and correlated significantly to shoulder pain at TI, at T2 and at T3 (p < 0.001). Moreover, GHS at admission accounted for nearly 50% of shoulder pain at T3 (adjusted R2 = 0.458; p < 0.001).

The objective of this review was to merge current treatment guidelines and best practice recommendations for management of neuropathic pain into a comprehensive algorithm for primary physicians. The algorithm covers assessment, multidisciplinary ...

This review summarizes the recent advances in glenohumeral subluxation (GHS) in hemiplegic patients and analyzes the reliability and validity of clinical evaluation and the effectiveness of different treatment approaches. GHS, a common complication of stroke, can be considered an important risk fact …

2025年3月19日 · Glutathione (GSH) is an antioxidant naturally produced by the liver and central nervous system. It is also available as a supplement. GSH is thought to help break down toxins and free radicals involved in cell damage, support immune function, and more. It also can play a role in treating certain genetic conditions.

Guidelines on the management of shoulder pain in general practice recommend corticosteroid injections (CSIs) as a treatment option if a more conservative treatment has been applied initially and failed. 1–4 It is estimated that in about 20–24% of patients with shoulder pain, CSIs are given as a treatment by general practitioners (GPs) 5–7 ...