
004353 - UBI-GFP Strain Details - The Jackson Laboratory
004353 C57BL/6-Tg(UBC-GFP)30Scha/J UBC-GFP transgenic mice express green fluorescent protein directed by the human ubiqutin C promoter, and were discovered to have transgene insertion on chromosome 17 resulting in linkage to H-2 b MHC haplotype (see details below).
Transgenic mice with green fluorescent protein-labeled ... - PubMed
We have generated transgenic mice that express green fluorescent protein (GFP) under the control of the mouse insulin I gene promoter (MIP). The MIP-GFP mice develop normally and are indistinguishable from control animals with respect to glucose …
007788 - Thy1-GFP line M Strain Details - The Jackson Laboratory
007788 STOCK Tg(Thy1-EGFP)MJrs/J These Thy1-GFP-M transgenic mice may be useful in neurobiological studies for fluorescent labeling of neural tissues, especially for mossy fibers in the cerebellum and intense, yet sparse, labeling of a variety of neuronal subsets.
006864 - MIP-GFP (line 1) Strain Details - The Jackson Laboratory
This mutant mouse strain may be useful in studies of diabetes and pancreatic beta islet cell biology. 006864 B6.Cg-Tg(Ins1-EGFP)1Hara/J <p>These "MIP-GFP" transgenic mice express Enhanced Green Fluorescent Protein (EGFP) under the control of the mouse insulin 1 promoter.
Cx3cr1-GFP小鼠 - shulb.com
Cx3cr1-GFP小鼠是一种在Cx3cr1基因座插入绿色荧光蛋白(GFP)基因的转基因小鼠模型。Cx3cr1(趋化因子受体3,与趋化因子CX3CL1配体结合)主要在单核细胞、巨噬细胞、微小胶质细胞和某些树突状细胞中表达。
小鼠大用处之荧光示踪小鼠 - 知乎 - 知乎专栏
为寻找激活褐色脂肪细胞的小分子物质,研究人员在褐色脂肪成熟标志物解偶联蛋白 (UCP1)终止密码子前定点敲入绿色荧光蛋白 (GFP)表达框,建立了成熟褐色脂肪组织细胞荧光示踪的小鼠模型(如图4所示)。 随后作者喂食荧光示踪小鼠1000余种临床用药通过观察荧光强度来检测体内Ucp1基因的表达水平,结果发现sutent能显著促进褐色脂肪细胞中UCP1的表达。 本研究结合荧光标记的基因示踪小鼠模型和大规模化合物筛选,建立了一个筛选调控褐色脂肪组织细胞激活剂 …
Generating green fluorescent mice by germline transmission …
1998年8月1日 · Here we demonstrate the superiority of our GFP transgenic mouse line for tagging the tetraploid compartment of an embryo. Through demonstrating some of the applications of the ubiquitous GFP reporter system in ES cells and the corresponding transgenic mouse line, we feel that the intensively evolving mouse genetic technologies will incorporate ...
Transgenic Mice Expressing Green Fluorescent Protein under the …
Here we describe the generation and validation of BAC transgenic mice expressing GFP under the transcriptional control of the CRH promoter, a new tool that may be used to characterize CRH function and connectivity within the brain. CRH-GFP mice are viable and fertile and appear grossly normal on physical inspection. This indicates that although ...
In Vivo Imaging of Cx3cr1gfp/gfp Reporter Mice with Spectral …
This protocol provides a detailed approach for generation of retinal B-scans, with SD-OCT, and imaging of microglia cell distribution in Cx3cr1 gfp/gfp mice with SLO in vivo, using an ophthalmic imaging platform system. The protocol can be used in several reporter mouse lines.
fosGFP Mouse: A Novel Transgenic Mouse for Identifying Subsets …
The fosGFP Mouse, carrying the c-fos gene coupled to GFP, thus expresses GFP when and wherever the c-fos gene is expressed. Using whole-cell recording techniques, this allows us to functionally identify individual cells (neurons) that are activated following a given stimulus or learning event, as well as detailed analysis of the types of ...