The most informative OCT parameters in differentiating preperimetric glaucoma included GCC average thickness, inferior quadrant RNFL thickness, inferior GCC thickness and superior GCC thickness. 11,65,66 Kim et al 45 suggested that GCC thickness appeared to be a better diagnostic biomarker for early glaucoma than did RNFL thickness.

2021年7月15日 · Many studies have shown GCC parameters to be a superior tool in early detection of glaucoma compared to those of the circumpapillary RNFL in patients with normal macular anatomy. 3-5 More specifically, one study reports that the most accurate GCC parameters for detecting early glaucomatous changes are average and inferior GCC thicknesses.- 3 ...

2022年12月7日 · 光学相干断层扫描（OCT）可以精确地测量黄斑区视网膜神经节细胞复合体（Ganglion cell complex, GCC）厚度，有研究发现, GCC厚度诊断青光眼的价值不低于RNFL厚度, 认为GCC厚度可以作为青光眼早期诊断的可靠指标之一。

2018年5月4日 · Optical coherence tomography (OCT) of the ganglion cell complex provides valuable information when evaluating patients with optic neuropathies, chiasmal or retrochiasmal visual field defects

光相干断层扫描（optical coherence tomography, OCT）作为一种新的组织横截面断层扫描影像学检查方法，分辨率高，能在活体实时显示视网膜组织的细微结构，可客观、定量地测量GCC及RNFL厚度，并有很好的重复性。

While the time-domain OCT devices were able to analyze only the total macular thickness, which is not correlated with a good accuracy in diagnosing glaucoma patients, the recent spectral-domain OCT (SD-OCT) devices allow the measurement of all three layers that form the macular GCC: macular retinal nerve fiber layer (mRNFL), GCL and IPL [9].

2020年5月6日 · The RTVue OCT provides the GCC map with additional parameters such as GLV (global loss volume) and FLV (focal loss volume), which can detect structural progression in early glaucoma.

2018年11月5日 · Recently, swept-source OCT (SS-OCT), a newer generation of OCT, has been introduced. Clinical assessment using multiple parameters, including peripapillary RNFL, ganglion cells, optic nerve head, and macular parameters, has proven useful for managing and diagnosing glaucoma as well as for evaluating risk in glaucoma suspects.

Various manufacturers of spectral-domain optical coherence tomography (SD-OCT) systems have released or will soon release software upgrades capable of measuring the thickness of the ganglion cell layer. The aims of this article are to introduce the technology and speculate on its future role in glaucoma management.

2022年2月16日 · Macular GCL and GCIPL thicknesses are equivalent for identifying early glaucoma with current OCT technology. This is likely explained by limitations of inner macular layer segmentation and concurrent changes within the inner plexiform layer in early glaucoma.