In several highly specialized plant-insect interactions, scent-mediated specificity of pollinator attraction is directed by the emission and detection of volatile organic compounds (VOCs). Although...

Several recent studies have underscored the benefit of using scent to detect cancer, and this paper will review the studies using animals to detect tumor scents. A large variety of animals have been used for this purpose-dogs, rodents, insects, and nematodes-and have shown their capacity to detect cancer, with a success rate close to 90%.

2022年1月1日 · We present here a quantitative review of 208 studies carried out between 1984 and 2020 that explore VOCs as potential biomarkers of cancers. We analyzed the main findings of these studies, listing and classifying VOCs related to different cancer types while considering both sampling methods and analysis techniques.

We used SPME fibres and gas chromatography - mass spectrometry to detect variations in cancer-related urinary VOCs over time. Results: This study allowed us to identify eight diagnostic biomarkers that help discriminate early stages of cancer tumour development (i.e., before MRI imaging techniques could identify it).

We analyzed the main findings of these studies, listing and classifying VOCs related to different cancer types while considering both sampling methods and analysis techniques. Considering this synthesis, we discuss several of the challenges and the most promising prospects of this research direction in the war against cancer.

2019年12月13日 · Conséquences écologiques, évolutives et appliquées des modifications d'odeurs corporelles associées au cancer. Laurent Dormont et Frédéric Thomas.

我们分析了基因工程肺腺癌小鼠模型中尿液的 VOC 成分，该模型具有致癌 EGFR 多西环素诱导的肺特异性表达。 我们比较了 10 只癌症小鼠和 10 只健康小鼠（对照组）在多西环素诱导前后的尿液 VOC，每两周一次，持续 12 周，直到出现全面的癌症。 我们使用 SPME 纤维和气相色谱-质谱法来检测与癌症相关的尿液 VOC 随时间的变化。 这项研究使我们能够识别八种诊断生物标志物，有助于区分癌症肿瘤发展的早期阶段（即在 MRI 成像技术可以识别它之前）。 对小鼠尿液 …

ORCID record for Flora Gouzerh. ORCID provides an identifier for individuals to use with their name as they engage in research, scholarship, and innovation activities.

In the framework of research targeting non-invasive methods to detect early stages of cancer development, this study asked whether untrained mice could detect odour changes in cancerous congeners.