Filopodia (sg.: filopodium) are slender cytoplasmic projections that extend beyond the leading edge of lamellipodia in migrating cells. [1] Within the lamellipodium, actin ribs are known as microspikes, and when they extend beyond the lamellipodia, they're known as filopodia. [2]

Filopodia，也就是细胞伪足，是在薄层结构基础上更向前探出去的爪。 在Filopodia的尖端往往都会有focal adhesion点状黏着（黏点）的存在。 Focal adhesion，可以想象成章鱼的吸盘，细胞为了粘住胞外结构的表面，就会形成一个个的黏着点，而在运动过程中，这些黏着点 ...

2008年5月9日 · Filopodia are thin, actin-rich, finger-like structures that are involved in numerous cellular processes, such as cell migration, wound healing, neurite outgrowth and embryonic development.

2024年7月4日 · Filopodia, widely distributed on cell surfaces, are distinguished by their dynamic extensions, playing pivotal roles in a myriad of biological processes. Their functions span from mechanosensing and guidance to cell–cell communication during …

2023年11月30日 · Filopodia are dynamic structures that are primarily composed of F-actin bundles and whose initiation and elongation are precisely regulated by the rate of actin filament assembly, convergence and cross-linking.

2001年8月21日 · Filopodia are thin, dynamic cell extensions comprising tight bundles of long actin filaments covered with cell membrane. They can change their length rapidly, span many cell diameters, and interact with other cells.

2024年5月8日 · Filopodia are generic structures present in virtually all cell types and are responsible for cellular activities such as spatial organization, motility, probing, and transport of molecules, vesicles, and viruses.

Filopodia are membrane-based actin-rich finger-like protrusions that are highly dynamic. Filopodia extend and retract rapidly from the cell surface as the cell explores its environment, seeking biological cues.

Filopodia are long, slender, actin-rich cellular protrusions, which recently have become a focus of cell biology research because of their proposed roles as sensory and exploratory organelles that allow for “intelligent” cell behavior. Actin nucleation, elongation and bundling are believed to be essential for filopodia formation and functions.

Filopodia are thin, actin-rich plasma-membrane protrusions that function as antennae for cells to probe their environment. Consequently, filopodia have an important role in cell migration, neurite outgrowth and wound healing and serve as precursors for dendritic spines in neurons.