
【第4期】马寄晓核医学教室 | PET历史和未来(2) - 搜狐
2020年7月2日 · 这种新的示踪剂——氟标记的脱氧葡萄糖(fluorodelxyglucose,FDG),是一种糖分子,用放射性核素18F标记,由于多种原因马上得到广泛应用。 其一,18F的半衰期远比其 …
[18F]FDG-6-P as a novel in vivo tool for imaging staphylococcal ...
2015年3月19日 · We have modified [18 F]FDG by phosphorylation, producing [18 F]FDG-6-P to facilitate specific uptake and accumulation by S. aureus through hexose phosphate …
The pivotal role of endoplasmic reticulum in FDG uptake in cancer …
2024年7月12日 · The rapid growth of PET imaging in oncology largely reflects the user-friendly kinetic features of 2-[18 F]-fluoro-2-deoxy-D-glucose (FDG). Sharing with glucose both GLUT …
肿瘤细胞的F18-FDG 代谢 - 简书
2018年12月26日 · 肿瘤细胞的f18-fdg 代谢 PET肿瘤显像剂很多,其中最为成熟而常用的是FDG。 尽管临床上为了提高诊断的准确性,常建议联合应用几种不同的肿瘤显像剂,但作为单一的肿 …
18F-fluoro-2-deoxy-d-glucose (FDG) uptake. What are we …
2021年4月16日 · This competition implies that the intracellular production of either 2DG-6-phosphate (6P) or FDG-6P is directly related to the generation rate of glucose-6P (G-6P). Both …
A fingerprint of 2-[18F]FDG radiometabolites – How tissue-specific ...
2023年11月17日 · Here we present a fingerprint of 2- [18 F]FDG radiometabolites over time in cancer cells, corresponding tumor xenografts and murine organs. Strikingly, radiometabolites …
Kinetic 18F-FDG PET/CT imaging of hepatocellular carcinoma: a …
2024年2月22日 · When 18 F-FDG enters tissues, hexokinase is phosphorylated to form 18 F-FDG-6P. Hexokinase is highly expressed in HCC, and k 3 is the phosphorylation rate. The …
Glucose transporter protein-independent tumor cell accumulation …
Metabolic analysis showed that [18F]AFDG was extremely stable in the incubation medium but was quickly hydrolyzed and metabolized to 2-fluoro-[18F]-2-deoxy-D-glucose-6-phosphate …
Mapping phosphorylation rate of fluoro-deoxy-glucose in rat …
2014年5月1日 · 19F magnetic resonance spectroscopy (MRS) studies of 2-fluoro-2-deoxy-d -glucose (FDG) and 2-fluoro-2-deoxy- d-glucose-6-phosphate (FDG-6P) can be used for …
Localized FDG loss in lung cancer lesions - EJNMMI Research
2024年11月1日 · Indeed, FDG shares with glucose both GLUT-facilitated transmembrane transport and hexokinase-catalyzed phosphorylation to FDG-6P that, in turn, irreversibly …
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