2025年2月21日 · Is There a “Fat Gene?” There’s one gene that’s getting a lot of attention, called FTO. Scientists found that people with certain differences in this gene have a 20% to 30% …

Fat mass and obesity-associated protein, also known as alpha-ketoglutarate-dependent dioxygenase FTO, is an enzyme that in humans is encoded by the FTO gene located on …

2021年9月23日 · In this Review, we summarize more than 20 years of genetic studies that have characterized the molecules and mechanisms that control body weight, specifically focusing …

2014年3月14日 · Now an international team of scientists has discovered that the obesity-associated elements within FTO interact with IRX3, a distant gene on the genome that …

Monogenic obesity is caused by variants of single genes while polygenic obesity includes several genes with the involvement of members of gene families. New advances in genetic testing …

2025年2月7日 · Genetics can play a role in having obesity. Twin studies have found the heritability of obesity to be approximately 40% to 75%. Up to 500 obesity-related genes have …

2023年11月1日 · Obesity has become a major health crisis in the past ∼50 years. The fat mass and obesity-associated (FTO) gene, identified by genome-wide association studies (GWAS), …

Research has identified genes associated with obesity in both humans and animals. For example, the DENND1B gene has been linked to obesity in Labrador retrievers and humans, …

The Fat mass and obesity associated (FTO) gene is a newly identified genetic factor for obesity. However, the exact molecular mechanisms responsible for the effect of FTO on obesity remain …

2024年6月27日 · The most well-known “fat gene,” FTO, explains less than 1 percent of the BMI difference. FTO codes for a brain protein influencing appetite, but its effect results in only a …