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2025年3月30日 · FPGT (Fucose-1-Phosphate Guanylyltransferase) is a Protein Coding gene. Among its related pathways are Synthesis of substrates in N-glycan biosythesis and Metabolism of proteins.Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and fucose-1-phosphate guanylyltransferase activity.

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Fucose-1-phosphate guanylyltransferase is an enzyme that in humans is encoded by the FPGT gene. [5] [6]L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell–cell recognition.The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose.

1-磷酸岩藻糖鸟苷酸转移酶： L-岩藻糖是糖蛋白和其他复杂碳水化合物中的关键糖，因为它可能参与这些大分子的许多功能作用，例如细胞间识别。这些岩藻糖基化寡糖的岩藻糖基供体是 GDP-β-L-岩藻糖。 GDP-岩藻糖的生物合成有两种替代途径；主要途径将 GDP-α-D-甘露糖转化为 GDP-β-L-岩藻糖。由该 ...

2024年12月10日 · Go to complete Gene record for FPGT; Go to Variation Viewer for FPGT variants; Summary. L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta ...

2014年1月1日 · The FPGT gene was first purified from pig kidneys, and a partial protein sequence was identified. Using this information, researchers at the A.D. Elbein laboratory were able to identify human cDNAs encoding a region similar to one of the pig FPGT peptides. Applying a PCR strategy with primers based on one of the human ESTs, the human cDNA was ...

FPGT fucose-1-phosphate guanylyltransferase [ (human)] Gene ID: 8790, updated on 8-Feb-2025. Summary. L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated ...

fpgt 底物是专为岩藻糖-1-磷酸鸟苷转移酶（fpgt）代谢而设计的化合物，fpgt 是岩藻糖代谢挽救途径中的一种关键酶。 这类底物对于旨在了解岩藻糖代谢过程的科学研究是不可或缺的，岩藻糖是一种对糖基化和细胞信号传导等各种细胞功能至关重要的糖。

Predicted to enable nucleotide binding activity and nucleotidyltransferase activity. Orthologous to human FPGT (fucose-1-phosphate guanylyltransferase). [provided by Alliance of Genome Resources, Apr 2022]