
Estrogen-related receptor gamma functions as a tumor ... - Nature
2018年5月15日 · In our current study, we identified estrogen-related receptor gamma (ESRRG; also known as ERRγ) as a potential tumor suppressor in GC by genomic analysis. ESRRG and its specific agonist, DY131,...
Estrogen-related receptor gamma regulates mitochondrial and …
2022年8月18日 · We demonstrate that deletion of ERRγ from DAergic neurons in adult mice was sufficient to cause a levodopa-responsive PD-like phenotype with reductions in mitochondrial gene expression and number,...
ESRRG Gene - GeneCards | ERR3 Protein | ERR3 Antibody
2025年3月30日 · ESRRG (Estrogen Related Receptor Gamma) is a Protein Coding gene. Diseases associated with ESRRG include Autism Spectrum Disorder and Amelogenesis Imperfecta, Type Ig. Among its related pathways are Gene …
Estrogen-related receptor gamma - Wikipedia
Estrogen-related receptor gamma (ERR-gamma), also known as NR3B3 (nuclear receptor subfamily 3, group B, member 3), is a nuclear receptor that in humans is encoded by the ESRRG (EStrogen Related Receptor Gamma) gene.
雌激素相关受体γ(ESRRG)基因 | MCE - MCE-生物活性分子 ...
该基因编码雌激素受体相关受体 (ESRR) 家族的成员,该家族属于核激素受体超家族。 ESRR 家族的所有成员共享一个几乎相同的 DNA 结合域,该域由两个 C4 型锌指基序组成。 ESRR 成员是孤儿核受体;它们与雌激素反应元件和类固醇生成因子 1 反应元件结合,并在没有任何配体的情况下激活由这两种反应元件控制的基因。 ESRR 家族与雌激素受体 (ER) 家族密切相关。 它们共享靶基因、协同调节因子和启动子,并且通过靶向同一组基因,ESRR 似乎以各种方式干扰 ER 介导 …
Estrogen-related receptor gamma implicated in a phenotype …
2016年7月6日 · ESRRG encodes estrogen-related receptor gamma (ERRγ), a dimeric orphan nuclear transcription factor that is a paralog to ERRβ, a known HL gene. 17, 18, 19 In addition, ESRRG has been shown by a...
ESRRG estrogen related receptor gamma - NIH Genetic Testing …
2024年6月19日 · Clinical resource with information about ESRRG, A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks., Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies., Gene-alcohol interactions ...
Estrogen-related receptor gamma is a regulator of mitochondrial ...
2025年3月1日 · Recent evidence indicates that the transcription factor estrogen-related receptor gamma (ERRγ/ Esrrg) is required for normal expression of mitochondrial, synaptic, and autophagy genes in neurons. Further, overexpression of Esrrg in dopaminergic neurons reduces synuclein load in the pre-formed fibril model of synucleinopathy.
ESRRG人源基因|ESRRG基因突变_致病性_靶点-RDDC官网
这个基因编码一个属于核激素受体超家族的雌激素受体相关受体(ESRR)家族的成员。 ESRR家族的所有成员都有一个几乎完全相同的DNA结合域,该域由两个C4型锌指模式组成。 ESRR成员是孤儿核受体;它们结合雌激素响应元素和类固醇激素因子1响应元素,并在没有配体的情况下激活由这两个响应元素控制的基因。 ESRR家族与雌激素受体(ER)家族有密切关系。 它们共享目标基因、共同调节物和启动子,并通过靶向同一组基因,ESRR似乎以各种方式干扰ER介导的雌 …
核受体雌激素相关受体γ通过调节Wnt/β-连环蛋白信号抑制结直肠 …
雌激素相关受体γ(esrrg)属于核受体家族,是调节基因转录的重要元件。 在我们的报告中,我们将 ESRRG 鉴定为潜在的肿瘤抑制因子。 ESRRG 水平降低最初是在 CRC 中观察到的,并且与不良预后高度相关。