Erythropoiesis-stimulating agents (ESA) are medications which stimulate the bone marrow to make red blood cells. [1] . They are used to treat anemia due to end stage kidney disease, chemotherapy, major surgery, or certain treatments in HIV/AIDS. [1][2] In these situations they decrease the need for blood transfusions. [2] .

市场上有2种EPO（3个品牌）可以用于危重病人的贫血症治疗。它们是 epoetin (Procrit(also known as Eprex), NeoRecormon) darbepoetin (Aranesp). PDpoetin(an erythropoietin produced in Iran by Pooyesh Darou pharmaceuticals) 最近的随机对照 临床试验 [4] 显示EPO并不改变

2025年1月7日 · Eprex or exogenous epoetin alfa binds to the erythropoietin receptor (EPO-R) and activates intracellular signal transduction pathways . The affinity (Kd) of EPO for its receptor on human cells is ∼100 to 200 pM .

2017年3月24日 · EPREX ® (epoetin alfa) is an erythreopoiesis-stimulating agent (ESA) that works by stimulating the production of red blood cells (RBCs). 6 ESAs are an important treatment option for patients with certain types of anaemia, including chemotherapy-induced anaemia and anaemia due to chronic kidney disease.

EPREX® is a sterile, preservative-free buffered protein solution of epoetin alfa (rch) in pre-filled syringes. The pre-filled syringes are fitted with the PROTECS™ needle guard device.

Eprex: Epoetin alfa belongs to the class of medications known as erythropoiesis regulating hormones. It is used to increase the production of red blood cells and decrease the need for transfusions of red blood cells.

2025年2月4日 · EPREX is indicated for the treatment of symptomatic anaemia (haemoglobin concentration of ≤10 g/dL) in adults with low- or intermediate-1-risk primary myelodysplastic syndromes (MDS) who have low serum erythropoietin (<200 mU/mL).

EPREX contains the active substance epoetin alfa -a protein that stimulates the bone marrow to produce more red blood cells which carry haemoglobin (a substance that transports oxygen). Epoetin alfa is a copy of the human protein erythropoietin (ee …

2024年8月1日 · EPREX is used to treat the anaemia associated with kidney disease. If you have kidney disease, your kidney may not produce enough erythropoietin (necessary for red blood cell production) and your doctor may wish to correct this by prescribing EPREX.

2025年1月24日 · EPREX vous est prescrit pour stimuler votre moelle osseuse afin de produire plus de globules rouges. · EPREX est utilisé dans le traitement de l’anémie chez les adultes recevant une chimiothérapie pour des tumeurs solides, un lymphome malin ou un myélome multiple (cancer de la moelle osseuse) et pouvant avoir besoin d’une transfusion ...