
Eph家族受体在机体生理和病理过程中作用机制的研究进展
摘要: 促红细胞生成素肝细胞激酶 (Erythropoietin-producing hepatocellular, Eph)受体家族作为目前已知最大的酪氨酸激酶受体家族,通过受体–配体结合,介导人类从胚胎发育到成人组织稳态诸多生物学功能的调节,参与机体各种免疫反应。 研究发现,Eph受体在包括神经系统发育、细胞迁移、血管形成等许多生理发育过程中起重要作用,在调节免疫反应、肿瘤、炎症、损伤修复等病理过程中也发挥着重要功能。 进一步深入的研究Eph家族受体的生物学功能能够更好的对临床疾病 …
Eph受体家族及其配体的信号转导途径及功能 - 豆丁网
2014年6月8日 · 摘要Eph受体是已知最大的酪氨酸蛋白激酶受体家族,Eph受体和其膜附着型配体(ephrin)在发育过程中呈 现不同的表达模式,近来研究证明,Eph受体和其配体在包括神经网络形成,神经管和轴旁中胚层的成型
Eph receptors and ephrins in cancer: bidirectional signalling and ...
The Eph receptor tyrosine kinases and their ephrin ligands have intriguing expression patterns in cancer cells and tumour blood vessels, which suggest important roles for their bidirectional signals in many aspects of cancer development and progression. Eph …
Ephs, Ephrins, Bidirectional Signaling | Learn Science at Scitable
Eph-ephrin signaling is their cellular traffic light. Consider the humble origin from which we all started: the fertilized egg. How do all vertebrates develop from that single-cell state to a new...
HOPITAL SIG - Etablissements Publics Hospitaliers Non …
Annuaire Algerie Consulter les informations (numéro de téléphone, adresse, google-map... etc) de HOPITAL SIG Etablissements Publics Hospitaliers Non Universitaires ( EPH ) à Mascara sur votre Annuaire des médecins spécialistes en algérie.
• The Eph receptors are the largest family of receptor tyrosine kinases. They bind glycosylphosphatidylinositol (GPI)-linked and transmembrane ephrin ligands, generating bidirectional signals at sites of cell–cell contact. • Eph receptors and/or ephrins are widely expressed in cancer cells and tumour
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Eph receptors and ephrins in cancer progression - PubMed
The involvement of the Eph system in tumour angiogenesis is well established, but recent findings also demonstrate roles in immune cells, cancer-associated fibroblasts and the extracellular matrix. Lastly, I discuss strategies under evaluation for therapeutic targeting of Eph receptors-ephrins in cancer and conclude with an outlook on promising ...
Eph Sig - Facebook
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Eph Sig Profiles - Facebook
View the profiles of people named Eph Sig. Join Facebook to connect with Eph Sig and others you may know. Facebook gives people the power to share and...