Enalapril is an antihypertensive agent that exhibits natriuretic and uricosuric properties. Enalapril lowers blood pressure in all grades of essential and renovascular hypertension, and peripheral vascular resistance without causing an increase in heart rate. 6 Individuals with low-renin hypertensive population were still responsive to enalapril.

2024年9月17日 · This activity focuses on various aspects of enalapril, including its indications, mechanism of action, adverse event profile, dosing considerations, monitoring strategies, and potential drug interactions, specifically emphasizing its crucial role as an effective agent in managing hypertension and associated disorders.

2024年3月1日 · Enalapril injection is used in adults to treat high blood pressure. Enalapril belongs to a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It works by decreasing certain chemicals that tighten the blood vessels, so blood flows more smoothly and the heart can pump blood more efficiently.

2025年3月1日 · Enalapril is an angiotensin converting enzyme (ACE) inhibitor. It works by blocking a substance in the body that causes the blood vessels to tighten. As a result, enalapril relaxes the blood vessels. This lowers blood pressure and increases the supply of blood and oxygen to the heart.

2020年2月17日 · Competitive inhibitor of angiotensin-converting enzyme (ACE); prevents conversion of angiotensin I to angiotensin II, a potent vasoconstrictor; results in lower levels of angiotensin II which causes an increase in plasma renin activity and a reduction in aldosterone secretion. 55% to 75% Prodrug, undergoes hepatic biotransformation to enalaprilat.

Enalapril, sold under the brand name Vasotec among others, is an ACE inhibitor medication used to treat high blood pressure, diabetic kidney disease, and heart failure. [5] For heart failure, it is generally used with a diuretic, such as furosemide. [6] It …

2024年5月30日 · How does enalapril work (mechanism of action)? Enalapril blocks the angiotensin-converting enzyme (ACE) from forming a hormone called angiotensin II. When angiotensin II binds to receptors,...

When given with hydrochlorothiazide, enalapril attenuates the secondary aldosteronism and ameliorates the hypokalaemia from diuretics. 3 Both acutely and chronically in patients with essential hypertension, enalapril reduced blood pressure with a rather flat dose-response curve.

2024年2月13日 · Enalapril maleate is a prominent angiotensin-converting enzyme inhibitor approved by the US Food and Drug Administration (FDA) for the treatment of heart failure, chronic hypertension, and asymptomatic left ventricular dysfunction. The FDA has approved a fixed-dose combination of enalapril with hydr …

Mechanism of action. Enalaprilat is the active metabolite of the orally available pro-drug, enalapril. Used in the treatment of hypertension, enalapril is an ACE inhibitor that prevents Angiotensin Converting Enzyme (ACE) from transforming angiotensin I into angiotensin II.