2025年3月28日 · EIF4A1 (Eukaryotic Translation Initiation Factor 4A1) is a Protein Coding gene. Diseases associated with EIF4A1 include Leukemia, Acute Myeloid and Hematologic Cancer. …

Eukaryotic initiation factor 4A-I (also known as eIF4A1 or DDX2A) is a 46 kDa cytosolic protein that, in humans, is encoded by the EIF4A1 gene, which is located on chromosome 17.

真核起始因子 4A （英語： eukaryotic translation Initiation Factor 4A，简称为 eIF4A）是一种 ATP 依赖性 RNA 结合蛋白，一种RNA依赖性 ATP酶，和一种RNA 解旋酶，它在 真核翻译 起始进 …

2024年11月8日 · Eukaryotic initiation factor 4 A (eIF4A) plays critical roles during translation initiation of cellular mRNAs by forming the cap-binding eIF4F complex, recruiting the 40S …

2025年1月8日 · eIF4A 是一种 ATP 依赖的 RNA 解旋酶，能够解开 mRNA 5’ 非翻译区（5’ untranslated region, 5’ UTR）的二级结构，帮助 43S 前起始复合物（preinitiation complex, …

eIF4A1 Is a Prognostic Marker and Actionable Target in Human Hepatocellular Carcinoma. eIF4A/PDCD4 Pathway, a Factor for Doxorubicin Chemoresistance in a Triple-Negative Breast …

2024年5月21日 · Here we show that eIF4A1 enhances translational repression during the inhibition of mechanistic target of rapamycin complex 1 (mTORC1), an essential kinase …

2025年3月25日 · All mRNAs require eukaryotic translation initiation factor (eIF) 4A1 for translation through its different functions: loading of the pre-initiation complex onto mRNAs and unwinding …

Enables double-stranded RNA binding activity. Predicted to be involved in cytoplasmic translational initiation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr …

In this review, we explored the predicted structures of the three eIF4A isoforms (eIF4A1, eIF4A2, and eIF4A3), and discussed possible explanations for which function during different …