2025年3月30日 · EFEMP2 (EGF Containing Fibulin Extracellular Matrix Protein 2) is a Protein Coding gene. Diseases associated with EFEMP2 include Cutis Laxa, Autosomal Recessive, …

已发现大量细胞外基质蛋白含有表皮生长因子 (EGF) 结构域的变异，并涉及多种功能，如血液凝固、补体激活和发育过程中细胞命运的确定。 该基因编码的蛋白质包含四个 EGF2 结构域和六 …

EGF-containing fibulin-like extracellular matrix protein 2 is a protein that in humans is encoded by the EFEMP2 gene. [4][5][6] A large number of extracellular matrix proteins have been found to …

2025年2月8日 · Whole-exome sequencing uncovers a novel EFEMP2 gene variant (c.C247T) associated with dominant nonsyndromic thoracic aortic aneurysm. EFEMP2 upregulates PD …

2023年7月7日 · The important role of PD-L1 in EFEMP2 promoting EMT progression and the inhibitory effect of EFEMP2 knockdown on the abdominal dissemination of ovarian cancer …

The EFEMP2 gene provides instructions for making a protein called EGF-containing fibulin extracellular matrix protein 2, which is also known as fibulin-4. Learn about this gene and …

2019年8月8日 · Epidermal growth factor-containing fibulin-like extracellular matrix protein 2 (EFEMP2), an extracellular matrix protein, is highly associated with tumor invasion and …

2025年1月4日 · EFEMP2 upregulates PD-L1 expression via EGFR/ERK1/2/c-Jun signaling to promote the invasion of ovarian cancer cells. Shen X, Jin X, Fang S, Chen JShen X, et al. Cell …

2024年3月1日 · Title: EFEMP2 increases the invasion ability of cervical cancer cells by promoting EMT via the Raf/MEK/ERK signaling pathway. Downregulation of fibulin-4 inhibits autophagy …

2024年9月4日 · They called the cDNA 'EGF-containing fibulin-like extracellular matrix protein-2' (EFEMP2) because of its significant homology to EFEMP1 (601548). Sequence analysis …