In regard to research, Dr. Santini combines his expertise in behavior neuroscience with patch-clamp electrophysiology to study the cellular mechanisms of fear conditioning and extinction. He focuses on the infralimbic (IL) sub-region of the medial prefrontal cortex (mPFC), a structure necessary for inhibiting conditioned fear responses ...

2012年4月18日 · Consistent with this, pharmacological inhibition of M-type K + channels enhances the intrinsic excitability of IL neurons and facilitated fear extinction (Santini and Porter, 2010).

Edwin SANTINI | Cited by 1,918 | of Palm Beach Atlantic University | Read 14 publications | Contact Edwin SANTINI

2010年8月12日 · For proper recall of extinction, various events must occur in IL including activation of NMDA receptors (Santini et al. 2001; Burgos-Robles et al. 2007), the mitogen-activated protein kinase pathway (Hugues et al. 2004), protein kinase A (Mueller et al. 2008), and protein synthesis (Santini et al. 2004). Our current findings show that recall of ...

2023年9月5日 · Dr. Edwin Santini and Vilmarie Degro united their lives and ministerial callings on December 8, 2001 in Ponce, Puerto Rico. Both congregated in the Christian Family Church. From a young age they were involved in the Ministry of Worship and Arts, leading the Ministry of Dance for more than 20 years.

2022年3月1日 · Tardy Vargas previously assisted in research conducted by pharmacy professors Dr. Adwoa Nornoo and Dr. Edwin Santini. She’s learned that as researchers test hypotheses, the results often bring surprises. “During that process,” she said, “you develop your critical thinking, and you can view things from a different perspective.

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Educational Background Ph.D.- Biomedical Sciences (Behavioral Neuroscience), Ponce School of Medicine (2004), Ponce, Puerto Rico B.A.- Biomedical Sciences, Interamerican University of Puerto Rico (1997), Ponce, Puerto Rico Assistant …

Semantic Scholar profile for Edwin Santini, with 1 scientific research papers. Skip to search form Skip to main content Skip to account menu. Semantic Scholar's Logo. Search 223,025,357 papers from all fields of science. Search. Sign In Create Free Account. Edwin Santini. Publications 1. h-index 0.

2010年9月15日 · Growing evidence indicates that the activity of infralimbic prefrontal cortex (IL) is critical for inhibiting inappropriate fear responses following extinction learning. Recently, we showed that fear conditioning and extinction alter the intrinsic excitability and bursting of IL pyramidal neurons in brain slices.