What is edoxaban? Edoxaban blocks the activity of certain clotting substances in the blood. Edoxaban is used to lower the risk of stroke caused by a blood clot in people with a heart rhythm disorder called atrial fibrillation. edoxaban is used when the atrial fibrillation is not caused by a heart valve problem.

Edoxaban is a direct, selective, reversible and competitive inhibitor of human factor Xa, with an inhibitory constant (K i) value of 0.561 nM. In coagulation, uninhibited factor Xa forms a prothrombinase complex with factor Va on platelet surfaces. Prothrombinases turn …

艾多沙班（通用名 Edoxaban，商品名 Lixiana，臺灣商品名 里先安）是一种口服Xa凝血因子直接抑制劑 [5] ，作为抗凝剂。 本藥物由 第一三共 开发，于 2011 年 7 月在日本获得批准用于预防下肢 骨科手术 后的静脉血栓。

Edoxaban is used to prevent serious blood clots from forming due to a certain irregular heartbeat (atrial fibrillation). It is also used to treat certain blood clots (such as in deep vein thrombosis -DVT or pulmonary embolus -PE). Edoxaban is an anticoagulant that works by blocking certain clotting proteins in your blood.

2023年8月25日 · Edoxaban belongs to the class of direct oral anticoagulants (DOACs) and is used for the treatment of pulmonary embolism (PE), deep venous thrombosis (DVT), and to reduce the risk of stroke and systemic embolism in patients with …

2025年2月1日 · Edoxaban is used to prevent stroke and blood clots in patients with a certain heart rhythm problem (eg, nonvalvular atrial fibrillation). Edoxaban is also used to treat deep venous thrombosis, a condition in which harmful blood clots form in the blood vessels of the legs.

2021年3月3日 · Edoxaban is an oral medication used to treat blood clots and reduce the risk of stroke in people with atrial fibrillation. Learn who it’s for and more.

Lixiana contains the active substance edoxaban. How is Lixiana used? Lixiana is available as tablets (15, 30 and 60 mg) and can only be obtained with a prescription. The usual dose is 60 mg once a day. Treatment is continued while the benefit outweighs the risk of bleeding, which depends on the condition being treated and any existing risk factors.

Edoxaban is a direct and reversible inhibitor of activated factor X (factor Xa), which prevents conversion of prothrombin to thrombin and prolongs clotting time, thereby reducing the risk of thrombus formation. 30 mg once daily. 60 mg once daily.

Indicated to reduce risk of stroke and systemic embolism associated with nonvalvular atrial fibrillation (NVAF) 60 mg PO qDay. Indicated for treatment of deep vein thrombosis (DVT) and...