ERCC4 is a protein designated as DNA repair endonuclease XPF that in humans is encoded by the ERCC4 gene. Together with ERCC1 , ERCC4 forms the ERCC1-XPF enzyme complex …

2024年12月25日 · ERCC4 (ERCC Excision Repair 4, Endonuclease Catalytic Subunit) is a Protein Coding gene. Diseases associated with ERCC4 include Fanconi Anemia, …

Variant ERCC4 genotypes are statistically significantly associated with benign breast disease, wspecially in women with a family history of breast cancer. XPF-ERCC1 controls TRF2 and …

该复合物是一种与 EME1 相互作用的结构特异性 DNA 修复核酸内切酶。 该基因的缺陷是导致着色性干皮病互补组 F (XP-F) 或着色性干皮病 VI (XP6) 的原因。 [RefSeq 提供，2009 年 3 月] …

2015年9月15日 · The ERCC1 and ERCC4 genes encode the two subunits of the ERCC1-XPF nuclease. This enzyme plays an important role in repair of DNA damage and in maintaining …

2019年4月3日 · The ERCC4 gene encodes a protein that together with ERCC1 make up the ERCC1-XPF 5-prime endonuclease. The XPF/ERCC1 endonuclease also plays a role in …

The ERCC1 and ERCC4 genes encode the two subunits of the ERCC1–XPF nuclease. This enzyme plays an important role in repair of DNA damage and in maintaining genomic stability. …

Title: The ZEB2-dependent EMT transcriptional programme drives therapy resistance by activating nucleotide excision repair genes ERCC1 and ERCC4 in colorectal cancer. F …

ERCC4 is an essential human gene in the nucleotide excision repair (NER) pathway, which is responsible for removing UV-C photoproducts and bulky adducts from DNA. Among the NER …

2024年10月10日 · Go to Variation Viewer for ERCC4 variants Summary The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during …