2021年10月20日 · Anabolic steroids are some of the more well-known PEDs. But erythropoietin (EPO)—a drug used to boost red blood cell counts in a practice called "blood doping"—falls under the same umbrella of forbidden substances. The drug has been a source of widespread abuse and controversy among professional cyclists since the 1980s. What Is Blood Doping?

Erythropoietin (/ ɪˌrɪθroʊˈpɔɪ.ɪtɪn, - rə -, - pɔɪˈɛtɪn, - ˈiːtɪn /; [1][2][3] EPO), also known as erythropoetin, haematopoietin, or haemopoietin, is a glycoprotein cytokine secreted mainly by the kidneys in response to cellular hypoxia; it stimulates red blood cell production (erythropoiesis) in the bone marrow.

2024年7月14日 · Erythropoiesis-stimulating agents (ESAs), such as epoetin, darbepoetin, and methoxy polyethylene glycol-epoetin β, are pharmacologically synthesized, recombinant forms of EPO. ESAs are indicated for conditions associated with impaired red blood cell production.

Erythropoietin is a glycoprotein that is produced by the kidneys and is commonly referred to as EPO. EPO is responsible for red blood cell production; the red blood cells are responsible for carrying oxygen to and through the blood.

2019年4月11日 · Blood doping, which may include the use of erythropoietin (EPO), is among the most well-known methods of doping in sport. Learn more about the prohibited method, as well as the prohibited substance EPO, in this anti-doping FAQ.

When Lance Armstrong admitted to cheating, he was admitting to blood doping, the act of artificially increasing your red blood cell count. This can be done through blood transfusions or by using EPO. Learn about the risks and side effects of blood doping, some of which can be fatal.

Blood doping is defined as the use of illicit products (e.g. erythropoietin (EPO), darbepoetin-alfa, hypoxia-inducible factor (HIF) stabilizers) and methods (e.g. increase aerobic capacity by maximizing the uptake of O 2) in order to enhance the O 2 transport of the body to the muscles.

2023年9月11日 · In medical practice, EPO injections are given to stimulate the production of red blood cells. For example, a synthetic EPO can be used to treat patients with anemia related to chronic or...

EPO is an erythropoiesis-stimulating agent (ESA) that is sold in recombinant form (rhEPO) for injection. It usually is packaged as a lyophilized (freeze dried) powder that is reconstituted with sterile water before injection. One popular form is called Epogen (r), and it is made for subcutaneous usage.

2019年3月20日 · Today, FDA-approved forms of EPO for humans include Epogen, Aranesp, Retacrit, and Procrit. When given to healthy people, however, the synthetic EPO boosts red blood cells to higher-than-normal...