2009年8月31日 · Here, we report that EBER induces signaling from the Toll-like receptor 3 (TLR3), which is a sensor of viral double-stranded RNA (dsRNA) and induces type I IFN and …

2015年9月9日 · We demonstrate in vivo that EBERs can interact with TLR3 and induce tumor cells to produce cytokines in B16 synergetic tumor and human NPC xenograft models, in …

2020年2月1日 · Epstein-Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) activation of NF-κB is pivotal for EBV-infected B lymphocyte survival. Herein, we found that LMP1 markedly …

2005年3月1日 · The EBV-induced gene 3 (EBI3) is expressed in dendritic cells (DCs) and part of the cytokine IL-27 that controls Th cell development. However, its regulated expression in DCs …

2015年9月15日 · We demonstrate in vivo that EBERs can interact with TLR3 and induce tumor cells to produce cytokines in B16 synergetic tumor and human NPC xenograft models, in …

2012年12月3日 · TLR3 is one category of TLR which interact specifically with double-stranded RNA (dsRNA) of viral origin. This binding leads in turn to MAPKs, NF-kB and IRF-3 activation …

2019年6月1日 · TLR3 and RIG-I mediate NPC angiogenesis triggered by EVs-derived EBERs. Viral noncoding RNAs (Epstein–Barr virus-encoded RNAs, EBERs) are believed to play a …

2024年4月17日 · Epstein-Barr virus (EBV), a Herpesviridae family member, is associated with an increased risk of autoimmune disease development in the host. We previously demonstrated …

Western blot analysis reveals intense expression of TLR3 in EBV-positive C666-1, C18, C17 and C15 xenografts/cell lines (A), and in EBV-negative HONE1 and CNE1 NPC cell lines (B).

2020年12月9日 · Epstein-Barr virus (EBV/HHV-4) is primarily transmitted via saliva. It proliferates in oropharyngeal epithelial cells, infects B lymphocytes, and enters the bloodstream to cause …