In humans, the DMD gene is located on the short (p) arm of the X chromosome between positions 21.2 and 21.1. Dystrophin is a rod-shaped cytoplasmic protein, and a vital part of a protein …

The dystrophin complex stabilizes the plasma membrane of striated muscle cells. Loss of function mutations in the genes encoding dystrophin, or the associated proteins, triggers instability of …

Dys是肌纤维膜细胞骨架的主要成分，与肌纤维膜蛋白紧密结合为抗肌萎缩蛋白结合蛋白，这些蛋白与细胞的层粘蛋白连接，Dys减少引起肌无力可能与这些联结失调有关。

2024年12月11日 · A structural study of native dystrophin glycoprotein complex from mouse skeletal muscle reveals an extended tower-like architecture that provides multiple binding sites …

2022年9月27日 · Dystrophin is the central protein of the dystrophin-glycoprotein complex (DGC) in skeletal and heart muscle cells. Dystrophin connects the actin cytoskeleton to the …

2024年12月2日 · The DMD gene and its protein products. The DMD gene is located at chromosome Xp21.2 and is responsible for Duchenne muscular dystrophy (DMD), the most …

2024年12月24日 · DMD (Dystrophin) is a Protein Coding gene. Diseases associated with DMD include Muscular Dystrophy, Duchenne Type and Muscular Dystrophy, Becker Type.Among its …

Dystrophin is a major component of the subsarcolemmal scaffold of muscle cells. It is a large rod-shaped cytoskeletal protein with four main functional domains that is localized at the …

Duchenne muscular dystrophy (DMD) is the most prevalent and severe form of human muscular dystrophy. While clinical descriptions of DMD date back to the 1850's, over 100 years passed …

2022年11月24日 · Introduction Dystrophin. Dystrophin is the largest known human gene and is located on the X chromosome (Tennyson et al., 1995).The gene contains 79 exons, codes for …