
DVL2 - Wikipedia
Segment polarity protein dishevelled homolog DVL-2 is a protein that in humans is encoded by the DVL2 gene. [5][6] This gene encodes a member of the dishevelled (dsh) protein family. …
DVL2 Gene - GeneCards | DVL2 Protein | DVL2 Antibody
Mar 28, 2025 · DVL2 (Dishevelled Segment Polarity Protein 2) is a Protein Coding gene. Diseases associated with DVL2 include Acyl-Coa Dehydrogenase, Very Long-Chain, …
初识Wnt信号通路 - 知乎 - 知乎专栏
Disheveled (Dsh) 蛋白(Dvl1、Dvl2 和 Dvl3)抑制糖原合成酶激酶-3β,从而增强 β-连环蛋白的稳定性 。Naked 可通过结合 Dsh 蛋白 并调控平面细胞极性通路的 Dsh 活性,从而抑制典型 …
北京大学JBC文章解析Wnt信号调控 - 生物通
Dishevelled (Dvl) is a central node of Wnt signaling. Insulin receptor substrates (IRSs), as critical component of insulin signaling, are involved in cell proliferation, metabolism and cancer …
DVL2 dishevelled segment polarity protein 2 [ Homo sapiens …
Feb 20, 2025 · Title: Dvl2 facilitates the coordination of NF-κB and Wnt signaling to promote colitis-associated colorectal progression. Targeting E3 Ubiquitin Ligase WWP1 Prevents …
散乱片段极性蛋白 2(DVL2)基因 | MCE - MCE-生物活性 ...
该基因编码一个 90-kD 的蛋白,该蛋白经过翻译后磷酸化形成一个 95-kD 的胞质蛋白,可能在多种 Wnt 蛋白介导的信号转导通路中发挥作用。 Wnt 信号传导中功能紊乱的机制可能在后生动物中 …
Superresolution microscopy localizes endogenous Dvl2 to Wnt ... - PNAS
We show that Dvl2 at endogenous protein levels forms “puncta” that mimic the behavior of biomolecular condensates. Dvl2_mEos3.2 dynamically localizes to non-membrane-bound, …
DVL2 dishevelled segment polarity protein 2 [ (human)]
Dvl2 could play a part in epithelial ovarian cancer progression and might be an independent prognostic factor. Additionally, it might be a prospective therapeutic target in the treatment of …
Ubiquitin-assisted phase separation of dishevelled-2 promotes …
Dec 15, 2022 · Dishvelled-2 (Dvl2) is an essential component of Wnt pathway, which controls several cell fate decisions during development, such as proliferation, survival and …
Reversible acetylation modulates dishevelled-2 puncta
Jul 6, 2020 · Dishevelled-2 (DVL2) is a central adaptor protein that propagates signals from upstream receptors to downstream effector β-catenin in canonical Wnt signaling.