About Flavoring-related Lung Disease - CDC
2024年4月23日 · Flavoring-related lung disease is caused by the flavoring chemical diacetyl (2,3-butanedione) and its substitute, 2,3-pentanedione (acetyl propionyl). Flavoring chemicals are used in food flavoring and production industries. Workers exposed to these flavoring chemicals are at risk of severe respiratory impairment.
Occupational Exposure to Diacetyl and 2,3-Pentanedione - CDC
Diacetyl and its substitute, 2,3-pentanedione, are widely used as flavoring compounds. The National Institute for Occupational Safety and Health (NIOSH) objective in establishing recommended exposure limits (RELs) for diacetyl and 2,3-pentanedione is to reduce the risk of respiratory impairment (decreased lung function) and the severe irreversible lung disease …
Exposure Control and Prevention | Flavoring-related Lung Disease …
2024年2月12日 · NIOSH recommends employers take steps to reduce occupational exposures to diacetyl and 2,3-pentanedione to below the recommended exposure limits (RELs). The RELs help reduce risks of respiratory impairment and obliterative bronchiolitis, the severe irreversible lung disease associated with occupational exposure to these chemicals.
Monitoring for Occupational Exposures to Diacetyl and 2,3 …
2015年7月13日 · Although these guidelines emphasize diacetyl, they can be applied to reduce exposures to diacetyl substitutes such as 2,3-pentanedione and other alpha-diketones. Best Practices: Engineering Controls, Work Practices, and Exposure Monitoring for Occupational Exposures to Diacetyl and 2,3-Pentanedione [PDF – 1.5 MB]
Using cross-sectional pulmonary function data from diacetyl exposed workers, NIOSH conducted analyses to determine the exposure-response relationship and identify risk of pulmonary function decrease at various levels of diacetyl exposure. NIOSH found that a relationship exists between diacetyl exposures and lower pulmonary function.
sure to diacetyl and 2,3-pentanedione and the potential for direct skin injuries from diacetyl and 2,3-pentanedione. A literature search was conducted through March 2021 to identify information on diacetyl and 2,3-pentanedione dermal absorption, acute toxicity, repeated-dose systemic toxicity, carcinogenicity, biolog-
Docket 245: Occupational Exposure to Diacetyl and 2,3 …
Previously, NIOSH held a public meeting on August 26, 2011 in Washington, DC to discuss and obtain comments on the draft document, “Criteria for a Recommended Standard: Occupational Exposure to Diacetyl and 2,3-Pentanedione” which was released in August 2011. Public comments on the draft document were received for submission to this docket ...
Health Effects of Vaping | Smoking and Tobacco Use | CDC
2024年5月15日 · Flavorings such as diacetyl, a chemical linked to a serious lung disease. Some flavorings used in e-cigarettes may be safe to eat but not to inhale because the lungs process substances differently than the gut.
of diacetyl could be inhibited or slowed down by storage in the dark at 5 °C. Standards prepared in amber volumetric flasks were stable for a couple days. Even with storage under these conditions, collected samples containing diacetyl were only stable for 7 days (95%). The average DE recovery for diacetyl was 90% over a range from 47 to 470 ...
About E-Cigarettes (Vapes) | Smoking and Tobacco Use | CDC
2024年10月24日 · Flavorings such as diacetyl, a chemical linked to a serious lung disease. Some flavorings used in e-cigarettes may be safe to eat but not to inhale because the lungs process substances differently than the gut. It is difficult to know which substances e-cigarettes contain.