2025年3月28日 · DHDH (Dihydrodiol Dehydrogenase) is a Protein Coding gene. Diseases associated with DHDH include Developmental Dysplasia Of The Hip 1 and Developmental Dysplasia Of The Hip 2. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity.

Dihydroorotate dehydrogenase (DHODH) is an enzyme that in humans is encoded by the DHODH gene on chromosome 16. The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone -mediated oxidation of dihydroorotate to orotate, in de …

2025年2月8日 · Survival was significantly better in gastric cancer patients with low DDH expression. Title: Overexpression of dihydrodiol dehydrogenase as a prognostic marker in …

2025年3月14日 · Through bioinformatics analysis, we found that a metabolic enzyme, dihydrodiol dehydrogenase (DHDH), which is highly expressed in nonimmune-inflamed TNBC, could deplete D-xylose in the tumor microenvironment to inactivate the immune response and cytotoxic T …

2024年8月16日 · CATALYTIC ACTIVITY: Trans-1,2-dihydrobenzene-1,2-diol + NADP (+) = catechol + NADPH. CATALYTIC ACTIVITY: D-xylose + NADP (+) = D-xylono-1,5-lactone + NADPH. SUBUNIT: Homodimer. TISSUE SPECIFICITY: Small intestine. SIMILARITY: Belongs to the Gfo/Idh/MocA family.

Official gene symbol, which is typically a short form of the gene name, according to HGNC. Assigned HPA protein class (es) for the encoded protein (s). Number of protein-coding transcripts from the gene as defined by Ensembl.

2025年2月8日 · Clinical resource with information about DHDH, and available tests. There are links to practice guidelines and authoritative resources like GeneReviews, PubMed, MedlinePlus, PharmGKB and clinicaltrials.gov.

2025年1月4日 · Gene ID: 27294, updated on 4-Jan-2025. This gene encodes an enzyme that belongs to the family of dihydrodiol dehydrogenases, which exist in multiple forms in mammalian tissues and are involved in the metabolism of xenobiotics and sugars.

Pubmed ID Year Title Citations; 23303836: 2013: Common variants of the ALDH2 and DHDH genes and the risk of Dupuytren's disease. 4: 24734329: 2013 [A coexistence of the Dupuytren's disease and malignant neoplasms: a review].

2019年4月2日 · DHODH is an enzyme that localizes to the inner mitochondrial membrane. It is the fourth and rate limiting step of the de novo pyrimidine synthesis pathway, converting dihydroorotate (DHO) to...