
The Role of Decorin in Autoimmune and Inflammatory Diseases
Decorin has been shown to be involved in wound repair, cell cycle, angiogenesis, tumor metastasis, and autophagy. Recent evidence indicates that it also plays a role in immune …
Decorin: A Guardian from the Matrix - PMC - PubMed Central (PMC)
Decorin, an archetypal member of the small leucine-rich proteoglycan gene family, has a broad binding repertoire that encompasses matrix structural components, such as collagens, and …
Decorin - an overview | ScienceDirect Topics
Decorin, first isolated from mammalian connective tissue, is one of the major small leucine-rich proteoglycans expressed ubiquitously (Kresse et al., 1993). Decorin, called also PG II, carries …
Decorin interacting network: A comprehensive analysis of decorin ...
Decorin, a prototype small leucine-rich proteoglycan, regulates a vast array of cellular processes including collagen fibrillogenesis, wound repair, angiostasis, tumor growth, and autophagy. …
Decorin: A Growth Factor Antagonist for Tumor Growth Inhibition
Decorin (DCN) is the best characterized member of the extracellular small leucine-rich proteoglycan family present in connective tissues, typically in association with or "decorating" …
Biological functions of decorin in cancer - PMC - National Center …
Accumulating evidence suggests that decorin affects the biology of various types of cancer by directly or indirectly targeting the signaling molecules involved in cell growth, survival, …
Decorin-mediated suppression of tumorigenesis, invasion, and
2021年1月15日 · Herein, we report that decorin (DCN), a small leucine-rich extracellular matrix proteoglycan, is downregulated in tumors from patients with IBC. Overexpression of DCN in …
The Role of Decorin in Autoimmune and Inflammatory Diseases
2022年8月17日 · Decorin has been shown to be involved in wound repair, cell cycle, angiogenesis, tumor metastasis, and autophagy. Recent evidence indicates that it also plays a …
Decorin: matrix-based pan-cancer tumor suppressor
2025年2月15日 · Studies have shown that decorin is a potent pan-cancer tumor suppressor that is under-expressed in most cancers. Decorin interacts with receptor tyrosine kinases and …
Decorin: a guardian from the matrix - PubMed
Decorin, an archetypal member of the small leucine-rich proteoglycan gene family, has a broad binding repertoire that encompasses matrix structural components, such as collagens, and …
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