2025年3月28日 · DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification.

DVL1, the human homolog of the Drosophila dishevelled gene (dsh), encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification.

DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation.

2022年5月19日 · We demonstrate that DVL1 and DVL3 are necessary for efficient proliferation in human myoblasts and are important for timely myogenic differentiation. DVL1 and DVL3 also contribute to regulation...

DVL1 gene mutations underlie a variant type of autosomal dominant Robinow syndrome called the osteosclerotic form, which features increased bone mineral density (osteosclerosis) affecting the bones of the skull. All of the identified DVL1 gene mutations occur in a region of the gene known as exon 14. Each mutation is predicted to remove a ...

DVL1 是果蝇蓬乱基因 (dsh) 的人类同系物，它编码一种细胞质磷蛋白，可调节细胞增殖，充当发育过程 (包括分割和成神经细胞规范) 的转导分子。 DVL1 是神经母细胞瘤转化的候选基因。

2025年1月10日 · DVL1基因，全名为dishevelled segment polarity protein 1，是我们身体中一个非常重要的基因。 它位于染色体1p36.33，主要参与细胞信号传导和发育过程。 DVL1基因的突变可能会导致一系列的生物学效应，从而影响我们的健康。

DVL1是果蝇的dishevelled基因（dsh）的人类同源基因，编码一种调节细胞增殖的胞质磷酸蛋白，作为发育过程（包括分节和神经母细胞特化）的转导分子。 DVL1是神经母细胞瘤转化的候选基因。

Dishevelled-1 (DVL-1) mediates Wnt signals critical for development and cellular homeostasis. DVL-1 is also linked with tumorigenesis, however its association with specific breast cancer (BC) subtypes and how it contributes to tumorigenicity remains poorly studied.

The DVL1 gene encodes dishevelled-1, a member of a family of intracellular scaffolding proteins that act downstream of transmembrane WNT (164820) receptors.