In molecular biology, the term double helix[1] refers to the structure formed by double-stranded molecules of nucleic acids such as DNA. The double helical structure of a nucleic acid complex arises as a consequence of its secondary structure, and is a fundamental component in determining its tertiary structure.

2024年10月24日 · DNA helicases unwind or separate the hydrogen bonds between nucleotides bases of two strands of double-stranded DNA by the use of the energy equivalent ATP. DNA helicases play mandatory roles in homologous somatic genome stability and meiotic mixing of the parental genomes in plants.

2025年2月22日 · Double helix, as related to genomics, is a term used to describe the physical structure of DNA. A DNA molecule is made up of two linked strands that wind around each other to resemble a twisted ladder in a helix-like shape.

There are three major families of DNA helices: A-DNA, B-DNA and Z-DNA. The helical structure of DNA is variable and depends on the sequence as well as the environment.

Clearly, the presence of two complementary strands is an efficient solution to the problem of the replication of DNA - how to make two exact copies from one original - but why is DNA helical? In fact, as this short tutorial aims to show you, the helix is a general response to the stacking up of single monomer units into a polymer - DNA can’t ...

Interactive image of nucleic acid structure (primary, secondary, tertiary, and quaternary) using DNA helices and examples from the VS ribozyme and telomerase and nucleosome. (PDB: ADNA, 1BNA, 4OCB, 4R4V, 1YMO, 1EQZ ) This article is about tertiary structure in nucleic acid.

2024年10月7日 · Explore the intricate structure of DNA's double helix, focusing on its unique features and the role they play in genetic function. DNA, the molecule that carries genetic information in living organisms, is renowned for its double helix structure.

In this review we discuss the biological consequences and therapeutic potential of triple helical DNA structures. We anticipate that the information provided will stimulate further investigations aimed toward improving DNA triplex-related gene targeting strategies for biotechnological and potential clinical applications.

2020年5月16日 · Double helix is the term used to describe the shape of our hereditary molecule, DNA. This instantly recognizable structure consists of two strands of DNA twisted around one another and connected in the center by hydrogen bonding. The hydrogen bonds form between nucleotides – the repeating unit of DNA and the language of the genetic code.

The DNA structure features a sugar-phosphate backbone with directionality (5' to 3') and folds into a double helix. There are three types of DNA helices: B (common), A (rare), and Z (left-handed). Understanding these structures is crucial for grasping DNA …