2020年2月2日 · When former heavyweight boxing champion Mike Tyson first tried 5-MeO-DMT — also called “the toad” — he said it knocked him off his feet, profoundly changing his life.

5-MeO-DMT (5-methoxy-N,N-dimethyltryptamine), also known as O-methylbufotenin or mebufotenin (INN), is a naturally occurring psychedelic of the tryptamine family. [5][1][4][2] It is found in a wide variety of plant species, and is also secreted by the glands of at least one toad species, the Colorado River toad. [5] .

2024年5月10日 · When threatened or startled, the Colorado River toad (also called the Sonoran desert toad) exudes 5-MeO-DMT, a hallucinogenic compound that discourages predators, from glands in its skin.

2023年6月26日 · Bufo alvarius is a species of toad living around creek beds and streams flowing through the Southern United States and Mexico. This toad secretes a venom through pores on its back that contains a high concentration of 5-MeO-DMT — one of the most potent psychedelics on Earth. Just a few milligrams of the venom is enough to completely blow your mind.

5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) is a naturally occurring tryptamine that primarily acts as an agonist at the 5‐HT1A and 5‐HT2A receptors, whereby affinity for the 5‐HT1A subtype is highest.

5-MeO-DMT is a psychoactive substance found in high concentrations in the bufotoxin of the Colorado River Toad (Bufo alvarius). Emerging evidence suggests that vaporized 5-MeO-DMT may occasion mystical experiences of comparable intensity to those occasioned by more widely studied psychedelics such as psilocybin, but no empirical study has ...

2023年12月14日 · 5-MeO-DMT is naturally-occurring — most predominantly found in a species of toad called Bufo alvarius (AKA the Colorado River Toad or the Sonoran Desert Toad). It’s also common in synthetic form, where it can be smoked, vaped, or insufflated (snorted). This psychedelic is notoriously fast-acting, but the effects are very short-lived.

2024年6月10日 · Found naturally in the Sonoran Desert toad, 5-MeO-DMT stands out for its quick, potent, and potentially life-altering psychedelic effects.

2022年8月23日 · The primary organic source of 5-MeO DMT is the Colorado River toad, also called the Sonoran Desert toad, native to northern Mexico and the southwest United States. When threatened, the toad excretes a milky white poison, called bufotoxin, from parotoid glands behind its …

2022年8月17日 · 5-Methoxy-N,N-dimethyltryptamine (commonly known as 5-MeO-DMT or Toad Medicine) is a naturally occurring psychedelic substance of the tryptamine class. As with its structural relatives DMT and 5-HO-DMT (Bufotenin), 5-MeO-DMT has been used as an entheogen by South American shamans for thousands of years and has recently been demonstrated to ...