DGAT2 Gene - GeneCards | DGAT2 Protein | DGAT2 Antibody
2025年3月28日 · DGAT2 (Diacylglycerol O-Acyltransferase 2) is a Protein Coding gene. Diseases associated with DGAT2 include Autosomal Dominant Charcot-Marie-Tooth Disease Type 2 …
The triglyceride-synthesizing enzyme diacylglycerol acyltransferase …
2024年9月6日 · In particular acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1), a rate-limiting enzyme in triglyceride synthesis, promotes early steps of virus assembly. The close proximity …
Diacylglycerol O-acyltransferase 2 - Wikipedia
Diacylglycerol O-acyltransferase 2 (DGAT2) is a protein that in humans is encoded by the DGAT2 gene. [5] This gene encodes one of two enzymes which catalyzes the final reaction in the …
DGAT2 inhibition blocks SREBP-1 cleavage and improves ... - Cell …
We found that DGAT2 deletion in hepatocytes or pharmacologic DGAT2 inhibition increased the phosphatidylethanolamine (PE) content of the ER, and this prevented SREBP-1 cleavage, …
Regulation of diacylglycerol acyltransferase 2 protein stability …
2014年5月12日 · Triacylglycerol (TG) is the major form of stored energy in eukaryotic organisms and is synthesized by diacylglycerol acyltransferase (DGAT) in the endoplasmic reticulum …
The Role of Diacylglycerol Acyltransferase (DGAT) 1 and 2 in
2018年3月21日 · Here, we show that inactivation of DGAT1 or DGAT2 in adult mouse heart results in a moderate suppression of TG synthesis and turnover. Partial inhibition of DGAT …
DGAT2 stability is increased in response to DGAT1 inhibition in …
2021年9月1日 · Endogenous DGAT2 in HepG2 cells was epitope tagged using gene editing. DGAT2 could be detected by immunoblotting with anti-FLAG. Endogenous DGAT2 is enriched …
Diacylglycerol Acyltransferase-2 (DGAT2) and Monoacylglycerol ...
Using co-immunoprecipitation experiments and an in situ proximity ligation assay, we found that DGAT2 interacted with monoacylglycerol acyltransferase (MGAT)-2, an enzyme that catalyzes …
二脂酰甘油酰基转移酶2 (DGAT2)基因研究进展 - 百度学术
二脂酰甘油酰基转移酶2 (Acyl CoA:Diacylgycerol Aeyltransferase 2,DGAT2)是生物体内的一种非常重要的酶,其主要机制是使二酰甘油加上脂肪酸酰基辅酶A以共价健结合形成三酰甘油.编码 …
Targeting diacylglycerol acyltransferase 2 for the treatment of ...
2019年11月27日 · Nonalcoholic steatohepatitis (NASH) is characterized by the accumulation of hepatocyte triglycerides, the synthesis of which is catalyzed by diacylglycerol acyltransferases …