Association of different pathologic subtypes of growth hormone ...
2021年9月16日 · Based on the GH granulation pattern in immunohistochemistry (IHC), two pathologic subtypes of GH-producing adenomas are densely granulated (DG) and sparsely granulated (SG) adenomas. About 30–50% of acromegaly patients have DG-GH adenomas with a diffuse positivity for GH [8, 9, 10].
Growth Hormone Tumor Histological Subtypes Predict Response …
Predictors of GH tumor response to different therapies have been incompletely defined based on histologic subtype, particularly densely (DG) versus sparsely (SG) granulated adenomas.
Clinical implications of growth hormone–secreting tumor subtypes
2012年3月21日 · Left DG growth hormone tumors may have an activating mutation in G protein subunit α (gsp), leading to constitutively active cAMP and PKA and resulting in high GH as a putative cause of excess growth hormone and acromegaly.
Association of different pathologic subtypes of growth hormone ...
2021年9月16日 · Based on the GH granulation pattern in immunohistochemistry (IHC), two pathologic subtypes of GH-producing adenomas are densely granulated (DG) and sparsely granulated (SG) adenomas. About 30–50% of acromegaly patients have DG-GH adenomas with a diffuse positivity for GH [8–10].
Safety of growth hormone (GH) treatment in GH deficient children …
Individuals surviving cancer and brain tumors may experience growth hormone (GH) deficiency as a result of tumor growth, surgical resection and/or radiotherapy involving the hypothalamic-pituitary region.
Surgical Management of GH-Secreting Pituitary Adenomas: An …
2001年9月1日 · Surgical management of acromegaly currently provides prompt, effective, and satisfactory initial treatment for the majority of patients. Using stringent criteria for remission, primary transsphenoidal surgery for GH-secreting pituitary adenomas is effective and often definitive therapy for acromegaly.
Different isoforms of growth hormone (20 kD-GH and 22 kD-GH
2022年2月22日 · There are two main types of growth hormone (GH) in the circulatory system. One is 22 kD-GH, which is the predominant isoform in the circulating system, 90% GH is present as a 22 kD protein, and 10% of GH is present as a 20 kD protein.
dong gui hu - Google Scholar
A novel polymorphism in a forkhead box A1 (FOXA1) binding site of the human UDP glucuronosyltransferase 2B17 gene modulates promoter activity and is associated with altered … DG Hu, D...
Février 2023 : Le bureau de la commission des structures de la CMEL a été mandaté par la Gouvernance du GHU AP-HP.Centre pour formuler des propositions sur le périmètre des DMU. Le travail a été conduit sur la base des remontées des questionnaires effectués en début d’année et notamment de ses verbatim.
广州大学
8月15日，高等教育评价机构软科正式发布了 “2024软科世界大学学术排名”，中国内地共有203所大学上榜，我校位列世界第417名，中国内地高校第78名，相比去年世界排名上升57位，中... 多图！ 黄埔院区风采大赏. 宽敞明亮！ 看广大新楼宇落成风采. 广州大学是以国家重要中心城市“广州”命名的综合性大学，于2000年合并组建，有着90多年的办学传统。...