Cyclins are proteins that control the progression of a cell through the cell cycle by activating cyclin-dependent kinases (CDK). [1] Cyclins were originally discovered by R. Timothy Hunt in 1982 while studying the cell cycle of sea urchins. [2][3]

2023年7月19日 · The cell cycle is regulated by cyclins, a type of protein that binds and activates cyclin dependent kinases (CDKs). Image Credit: Andrii Vodolazhskyi / Shutterstock. The accurate transmission of...

Cyclins are regulatory proteins that play a critical role in the regulation of the cell cycle by binding and activating CDKs. Cyclins were originally discovered as proteins that oscillate in a cyclic pattern during the cell cycle, with different cyclins being produced and degraded at different stages of the cell cycle [19].

Some of the cyclins exhibit unique patterns of expression in germ cells that suggest possible concomitant distinct functions, predictions that are being explored by targeted mutagenesis in mouse models. A novel, meiosis-specific function has been shown for …

The cyclin-dependent kinases (CDKs) are a family of serine/threonine kinases controlling progression through the cell cycle. 1 The regulatory subunits of the CDKs, known as cyclins, form complexes with their catalytic partner to function as checkpoint kinases of specific proteins that regulate progression through the cell cycle.

2025年2月26日 · The cyclins, cyclin-dependent kinases (CDKs), CDK inhibitors (CKIs), and checkpoint proteins are examples of these internal signals that keep an eye on cellular parameters like cell growth, chromosome alignment, and DNA integrity.

2025年1月12日 · Cyclins are a family of proteins that regulate the progression of the cell cycle by binding to cyclin-dependent kinases (CDKs). They control the timing and coordination of various cellular activities.

Cyclins are a group of proteins that control the progression of the cell cycle by activating particular enzymes—cyclin dependent kinases. Those kinases act on different protein structures that play large roles in the cell cycle.

Cyclins are proteins whose concentration in the cells increases and decreases in phase with the cell cycle. Passage through the cycle is controlled by cyclin-dependent kynase complexes which are inactive unless associated with a cyclin.

Cyclins are proteins that regulate the progression of the cell cycle by activating cyclin-dependent kinases (CDKs). They ensure that cell cycle events occur in the correct sequence and at the appropriate time.