肿瘤微环境中的新秀：CXCL13+ T细胞 - 知乎 - 知乎专栏
肿瘤浸润T细胞表达CXCL13首次进入科学家的视野是在2019年发表的一篇Cell上，篇名为：“Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment …
CXCL13/CXCR5 signaling axis in cancer - PubMed
2019年6月15日 · CXCL13/CXCR5 signaling axis makes pivotal contributions to the development and progression of several human cancers. In this review, we discuss how CXCL13/CXCR5 …
CXCL13: a common target for immune-mediated inflammatory …
CXCL13 is a chemokine that plays an important role in the regulation and development of secondary lymphoid organs. CXCL13 is also involved in the regulation of pathological …
CXCL13 and Its Receptor CXCR5 in Cancer: Inflammation, …
2021年7月19日 · Originally identified as a B-cell chemoattractant, CXCL13 exerts important functions in lymphoid neogenesis, and has been widely implicated in the pathogenesis of a …
Role of the CXCL13/CXCR5 Axis in Autoimmune Diseases - PMC
CXCL13 is a B-cell chemokine produced mainly by mesenchymal lymphoid tissue organizer cells, follicular dendritic cells, and human T follicular helper cells. By binding to its receptor, CXCR5, …
CXCL13-CXCR5 axis: Regulation in inflammatory diseases and cancer
Chemokine C-X-C motif ligand 13 (CXCL13), originally identified as a B-cell chemokine, plays an important role in the immune system. The interaction between CXCL13 and its receptor, the G …
Nature Cancer | 张泽民课题组揭示肿瘤特异T细胞特征及多癌种水 …
2022年9月23日 · 通过对公共数据集的分析，该研究提出了基于CXCL13表达水平识别免疫检查点阻断（ICB）治疗前后肿瘤微环境中肿瘤抗原特异T细胞的方法，鉴定了肿瘤特异CD8 T细胞的 …
趋化因子CXCL13及其受体CXCR5在疾病中的研究进展
趋化因子通过与其受体相互作用，发挥招募免疫细胞、活化淋巴细胞和激活炎症反应等功能。 近年来，大量研究证明趋化因子CXCL13及其受体CXCR5与自身免疫病及肿瘤的生长、侵袭和转移 …
CXCL13-CXCR5 axis: Regulation in inflammatory diseases and cancer
2022年9月1日 · Chemokine C-X-C motif ligand 13 (CXCL13), originally identified as a B-cell chemokine, plays an important role in the immune system. The interaction b…
什么是趋化因子CXC配体13(CXCL13)？ - 知乎
趋化因子CXC配体13 (CXCL13)也称为 B淋巴细胞趋化因子 (BLC)或BCA-1，高水平表达于人的肝脏、脾脏、淋巴结和肠道中。 它选择性地对属于B-1和B-2亚群的B细胞产生趋化作用，通过与 …