Activators and Inhibitors of Protein Kinase C (PKC): Their …
Protein kinase C (PKC), a family of phospholipid-dependent serine/threonine kinase, is classed into three subfamilies based on their structural and activation characteristics: conventional or …
蛋白激酶C - 百度百科
蛋白激酶C是 G蛋白偶联受体 系统中的 效应物, 在非活性状态下是 水溶性 的，游离存在于 胞质溶胶 中，激活后成为膜结合的酶。 蛋白激酶C的激活是脂 依赖性 的，需要膜脂 DAG 的存在， …
Protein kinase C - Wikipedia
In cell biology, protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling the function of other proteins through …
Protein kinase C, an elusive therapeutic target? - Nature
2012年11月30日 · Protein kinase C (PKC) has been a tantalizing target for drug discovery ever since it was first identified as the receptor for the tumour promoter phorbol ester in 1982.
PKC 通路 | Cell Signaling Technology
蛋白激酶 C (PKC) 家族成员调控大量的细胞反应，包括基因表达、蛋白分泌、细胞增殖和炎性反应。 其基本的蛋白结构包括一个 N 端调节区，该调节区由一个铰链区连接至 C 端激酶区域。 …
Protein kinase C (PKC) isozyme-specific substrates and their design
Protein kinase C (PKC), a phospholipid-dependent serine/threonine kinase, appears to be involved in the signal transduction response to many hormones and growth factors; there are …
Dynamics and membrane interactions of protein kinase C - PMC
Protein Kinase C (PKC) is a family of Ser/Thr kinases that regulate a multitude of cellular processes through participation in the phosphoinositide signaling pathway. Significant …
PKC-delta and PKC-epsilon: Foes of the same family or strangers?
2011年11月1日 · Protein kinase C (PKC) is a family of 10 serine/threonine kinases divided into 3 subfamilies, classical, novel and atypical classes. Two PKC isozymes of the novel group, …
Regulation of Protein Kinase C function by ... - ScienceDirect
2011年5月1日 · Protein Kinase C (PKC) is a family of serine/threonine kinases whose function is influenced by phosphorylation. In particular, three conserved phosphorylation sites known as …
Discovery of a small-molecule protein kinase Cδ-selective ... - Nature
2018年1月18日 · Protein kinase C (PKC) isozymes play major roles in human diseases, including cancer. Yet, the poor understanding of isozymes-specific functions and the limited...