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Meta-analysis of the make-up and properties of in vitro models of …
2024年9月20日 · Here we report a meta-analysis of the make-up and properties of transwell and microfluidic models of the healthy BBB and of BBBs in glioblastoma, Alzheimer’s disease, …
A human pluripotent stem cell-derived in vitro model of the …
2024年5月1日 · Using human induced pluripotent stem cell-derived brain microvascular endothelial cells (hiPSC-BMECs), we aimed to develop a novel in vitro model of the BBB in …
血脑屏障体外模型的评价指标 - 知乎
检测SLCs、ABC转运体的表达可用于评价BBB体外模型的渗透性。 1.渗透性检测待细胞形成致密单层之后,对模型进行通透性检测实验。 Transwell上室加入0.5 mg/mL的FITC-葡聚糖溶液 ( …
基于平行人工膜渗透分析法对药物跨血脑屏障渗透性的仿生系统优 …
2023年2月1日 · 血脑屏障 (blood-brain barrier,BBB) 是脑毛细血管阻止某些物质进入脑循环血,从而保持脑组织内环境基本稳定的一种特殊结构 [1],其对维持脑部内环境稳态具有重要作 …
血脑屏障:中枢药物研发之痛 - CNS药物开发中的DMPK评价 - 药 …
2020年9月8日 · 血脑屏障(Blood-brain barrier,BBB)指脑毛细血管壁与神经胶质细胞形成的血液与脑组织之间的屏障,其主要由血管内皮细胞(Endothelial cells)(细胞之间通过紧密连 …
大鼠脑微血管内皮细胞与周细胞、星形胶质细胞共培养建立体外血 …
摘要: 目的 应用原代培养的大鼠脑微血管内皮细胞 (brain-microvessel endothelial cells,BMECs)与脑微血管周细胞 (brain-microvessel pericytes,BMPC)、星形胶质细胞 (astrocytes,AS)共培养 …
CM Heating | BBB Business Profile | Better Business Bureau
CM Heating Inc offers heating, cooling, fire place and water heater sales, installation and maintenance services. This business is in an industry that may require professional licensing,...
基于 hCMEC/D3 细胞的血脑屏障 (BBB) 体外模型综述。,Journal of …
2023年4月29日 · 在不同的模型中,永生化人细胞系 hCMEC/D3 具有高通量、可重复性、同源性和低成本等特点,有可能用于标准化的体外 BBB 模型。 该模型中细胞旁通路的高渗透性和某些 …