It functions as a pattern-recognition receptor for a variety of β-1,3-linked and β-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Expression is …

2025年3月28日 · CLEC7A (C-Type Lectin Domain Containing 7A) is a Protein Coding gene. Diseases associated with CLEC7A include Aspergillosis and Candidiasis, Familial, 4. Among …

2011年4月27日 · Dectin-1 (also known as CLEC7A) is a pattern-recognition receptor expressed by myeloid phagocytes (macrophages, dendritic cells and neutrophils) that detects β-glucans …

2025年2月8日 · CLEC7A regulates M2 macrophages to suppress the immune microenvironment and implies poorer prognosis of glioma. Possible role of intestinal fungal dysbiosis in dectin-1 …

CLEC7A also known as DECTIN1, is a type II membrane receptor with an extracellular C type lectin receptor and an ITAM intracellular region.

2023年6月8日 · Single-cell RNA-sequencing analysis of microglia from an AD mouse model identifies Stat1 and Clec2d as pre-MGnD markers. This phenotypic transition enhances …

Clec7a is a pattern recognition receptor involved in neuroinflammation. The higher expression of Clec7a was observed in the substantia nigra (SN) and striatum of PD rats with dopaminergic …

Clinical resource with information about CLEC7A, Aspergillosis, susceptibility to, Familial chronic mucocutaneous candidiasis, and available tests. There are links to practice guidelines and …

2024年2月5日 · It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate …

2024年12月23日 · CLEC7A knockdown was found to promote cell viability in BV2 cells and inhibiting pyroptosis in HT22 cells. CLEC7A knockdown in microglia also decreased infarct …