Cicutoxin is a naturally-occurring poisonous chemical compound produced by several plants from the family Apiaceae including water hemlock (Cicuta species) and water dropwort (Oenanthe …

Cicutoxin (a C17-polyene), has been shown to be a potent blocker of potassium channels of T lymphocytes. A similar action on potassium channels of neurons could account for the central …

Cicutoxin is an unsaturated aliphatic alcohol which is postulated to exert toxicity by central cholinergic stimulation. Specifically, stimulation of both nicotinic and muscarinic receptors …

Mechanisms of toxicity: The principal toxins, cicutoxin and oenanthotoxin, belong to a group of C17 conjugated polyacetylenes. They act as (noncompetitive) gamma-aminobutyric acid …

Cicutoxin 是一种强效 GABA 拮抗剂，可诱 发惊厥反复发作并发挥胆碱能作用。 Cicutoxin 主要作用于大脑和骨骼肌。 Cicutoxin 可从 Cicuta maculata 和 Cicuta douglasii 中分离出来。 …

Cicutoxin is a potent GABA antagonist that induces recurrent seizures and exerts cholinergic effects. Cicutoxin acts primarily on the brain and skeletal muscles. Cicutoxin can be isolated …

Properties: Prisms from ether + petr ether, transformed in air and light to yellow oily resin. mp 54°. [a]D15 -14.5° (c = 1.7 in ethanol). Sol in alc, chloroform, ether, hot water, alkali hydroxides. …

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Development and applications of highly selective palladium-catalyzed monocoupling reactions of (cyclo)alkenes and 1,3-alkadienes bearing two or three electrophilic sites and bis (enol …

2009年3月1日 · Cicutoxin (Figure 1), a major toxic component of water hemlock (Cicuta virosa and Cicuta maculate), [1–3] belongs to the class of C 17-polyacetylenes bearing a long π …