
Chromones as a privileged scaffold in drug discovery: A review
2014年5月6日 · Chromone (1) (4H-chromen-4-one, 4H-1-benzopyran-4-one) is an important class of oxygen-containing heterocyclic compounds with a benzoannelated γ-pyrone ring and they …
Chromone - an overview | ScienceDirect Topics
2011年7月7日 · Chromone 1 was prepared by condensation of the 2′-hydroxyacetophenone with ethyl formate in the presence of sodium hydride in THF followed by dehydration of the …
Recent advances in the synthesis of 4H-chromen-4-ones (2012 − …
2022年1月1日 · Chromones is a family of oxygen heterocyclic compounds whose synthetic versatility and broad spectrum of bioactive properties has been widely reported…
An update on the advances in chromone and the derivatives …
2024年12月19日 · In 2022, Yu and collaborators successfully developed an iodine-promoted tandem vinyl α-C-H bond phosphorothiolation and chromone cyclization reaction involving o …
Recent advances in the diversification of chromones and flavones …
2020年12月1日 · Chromone and flavone are both central backbones of natural products and clinical medicines. Synthesis of diversely functionalized chromones and flavones constitutes …
Chromone - an overview | ScienceDirect Topics
The chromone motif features in a number of natural products: especially abundant are the flavones (2-arylchromones) and isoflavones (3-arylchromones). A range of biological activities …
Synthetic strategies and pharmacological activities of chromene …
2022年9月5日 · The chromone (Scheme 17) 55 was formed by condensation of 2-hydroxy acetophenone 53 with N,N-dimethylformamide dimethyl acetal 54 under MW irradiation and in …
Chromone, A Privileged Scaffold in Drug Discovery: Developments …
Details of diverse biological activities of chromone derviatives, such as anti-cancer, antimicrobial, anti-viral, anti-inflammatory, antioxidant, as Monoamine Oxidase-B (MAO-B) inhibitors, anti …
Synthesis, docking and biological activities of novel chromone …
2021年4月1日 · A series of chromone linked [1,2,3]-triazoles were designed based on literature followed by in silico studies. The in silico studies indicated good docking score for (2E)-(1R …
Synthesis and biological evaluation of chromone-thiazolidine-2,4 …
2023年11月1日 · A series of chromone-thiazolidine-2,4-dione derivatives (e1 ∼ 28) were synthesized and screened for their α-glucosidase inhibitory. All synthetic derivatives presented …