Chalcone is the organic compound C 6 H 5 C(O)CH=CHC 6 H 5. It is an α,β-unsaturated ketone. A variety of important biological compounds are known collectively as chalcones or chalconoids. [3] They are widely known bioactive substances, fluorescent materials, and …

Chalcone is a member of the class of chalcones that is acetophenone in which one of the methyl hydrogens has been replaced by a benzylidene group. It has a role as a plant metabolite. It is a member of styrenes and a member of chalcones.

查耳酮（Chalcone）是一种α,β-不饱和羰基化合物的芳香 酮，可作为各种重要的生物化合物的核心，统称为 查耳酮类化合物 （ 英语 ： Chalconoid ） 。亚苄基苯乙酮是查耳酮系列的骨架。

2020年1月6日 · Chalcone is an aromatic ketone that forms the central core of many important biological compounds, which are known as chalcones. Chalcones are the biogenetic precursors of flavonoids and isoflavonoids, which are abundant in plants. Chalcones are active lead molecules in medicinal chemistry for the discovery of new drugs.

After a careful literature search, it has been found that in the past decade many scientific developments took place in chalcone chemistry, which is scattered in nature. Furthermore, heterocyclic rings are known to be bioactive, and incorporating heterocyclic moieties in the structural framework of chalcones will further increase their bioactivity.

A chalcone is a simple chemical scaffold of many naturally occurring compounds and has a widespread distribution in vegetables, fruits, teas, and other plants. 1–5 The word “chalcone” is derived from the Greek word “chalcos”, meaning “bronze”, which results from the colors of most natural chalcones. 3 Chalcone compounds have a ...

2021年8月13日 · This review article aims to demonstrate how bioinspired synthesis of chalcone derivatives can potentially introduce a new chemical space for exploitation for new drug discovery, justifying the title of this article.

Multifaceted and complex underlying mechanisms of chalcone actions demonstrated their ability to modulate a number of cancer cell lines, to inhibit a number of pathological microorganisms and parasites, and to control a number of signaling molecules and cascades related to …

2022年10月19日 · The presence of the reactive α,β-unsaturated system in the chalcone’s rings showed different potential pharmacological properties, including inhibitory activity on enzymes, anticancer, anti-inflammatory, antibacterial, antifungal, …

2023年1月1日 · Chalcone has a variety of biological activities, including anticancer, antiinflammatory, antioxidant, antineurodegenerative, antimalarial, antibacterial, antiviral and antidiabetic properties. Owing to its diverse activity and relatively simple chemical synthesis, chalcone is widely used as a privileged scaffold in molecular hybridization ...