Cefpirome is a fourth-generation cephalosporin. Trade names include Cefrom, Keiten, Broact, and Cefir. Cefpirome is considered highly active against Gram-negative bacteria, including Pseudomonas aeruginosa, and Gram-positive bacteria. [citation needed]

硫酸头孢匹罗是一种最新型的头孢菌素类抗生素，该药由德国Hoechst研制成功，并于1992首先在墨西哥、瑞典上市，商品名Cefrom。 抗菌谱广，抗菌活性强，对金葡菌的抗菌作用与头孢替安相同；对绿脓杆菌与哌拉西林、庆大霉素相似。 对β-内酰胺酶，包括各种质体介导的青霉素酶和染色体介导的头孢菌素酶. 都很稳定。 用于败血症及严重的尿道感染，呼吸道感染等。 [2] 为第四代头孢菌素，对多种β-内酰胺酶稳定，对临床主要致病菌的抗菌活性较许多第三代头孢菌素强，对 …

It is a cyclopentapyridine and a cephalosporin. Cefpirome is a semisynthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity. Cefpirome binds to and inactivates penicillin -binding proteins (PBPs) located on the inner membrane of the bacterial cell wall.

2025年1月7日 · Cefpirome binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell …

Cefpirome is an injectable extended-spectrum or 'fourth generation' cephalosporin. Its antibacterial activity encompasses many of the pathogens involved in hospital-acquired infections such as Enterobacteriaceae, methicillin-susceptible Staphylococcus aureus, coagulase-negative staphylococci and vir …

头孢匹罗（英语：Cefpirome）是第四代头孢菌素，商品名包括Cefrom、Keiten、Broact和Cefir。 头孢匹罗被认为对 革兰氏阴性菌 （包括 铜绿假单胞菌 ）和 革兰氏阳性菌 具有高度活性。

Cefpirome is an antibiotic indicated in the treatment of a wide variety of infections in the body. The next evolution of DrugBank is here. Designed for scientists, driven by AI, and powered by real-time insights. This is drug intelligence, redefined. Build, train, & validate predictive machine-learning models with structured datasets.

用于敏感菌所引起的各种感染，主要用于维治性感染如金葡菌、肠杆菌属及绿脓杆菌引起的呼吸道感染。 [2] 总收率可达25%。 7-氨基-3-氯甲基-3-头孢-4-羧酸二苯甲基酯盐酸盐 (I，50g，0.11mo1)悬浮于400ml乙酸乙酯和150ml水的混合液中，在冰浴冷却下，加入200ml lmol/L氢氧化钠溶液。 加毕，继续搅拌30min，得到澄清的二相溶液。 分出乙酸乙酯层。 用300ml水洗，100g无水硫酸钠干燥。 该乙酸乙酯溶液 (不移去硫酸钠)和苯甲醛 …

2014年1月1日 · Cefpirome is a fourth-generation cephalosporin with good in-vitro activity against both Gram-positive and Gram-negative aerobes, including Pseudomonas spp.

2012年11月29日 · Cefpirome is an injectable extended-spectrum or ‘fourth generation’ cephalosporin. Its antibacterial activity encompasses many of the pathogens involved in hospital-acquired infections such as Enterobacteriaceae, methicillin-susceptible Staphylococcus aureus, coagulase-negative staphylococci and viridans group streptococci.