Cyclin-dependent kinase 5 - Wikipedia
The enzyme is involved in many aspects of neuronal development and functions. The main role of Cdk5 when it comes to neurons is to assure proper neuronal migration. Neurons will send out …
CDK5_百度百科
Ckd5是作为一种多功能激酶，其主要功能是参与神经细胞迁移、轴突导向、突触发生与传递，近年来研究发现，CDK5在多种组织中表达，它可以通过磷酸化不同的调节底物发挥多种生物学作 …
CDK5 Gene - GeneCards | CDK5 Protein | CDK5 Antibody
2025年3月30日 · CDK5 (Cyclin Dependent Kinase 5) is a Protein Coding gene. Diseases associated with CDK5 include Lissencephaly 7 With Cerebellar Hypoplasia and …
CDK5: Key Regulator of Apoptosis and Cell Survival - PubMed
2019年11月6日 · Treatment with the CDK5 inhibitor roscovitine sensitizes cells to heat-induced apoptosis and its phosphorylation, which results in prevention of the apoptotic protein …
CDK5–cyclin B1 regulates mitotic fidelity - Nature
2024年9月4日 · CDK5 is an atypical CDK owing to its high expression in post-mitotic neurons and activation by non-cyclin proteins p35 and p392.
厦门大学揭示神经发育与退行性疾病关键激酶CDK5的全新调控机理
CDK5是细胞周期蛋白激酶家族中的一个特殊成员。 与其它细胞周期蛋白激酶均由Cyclin所激活不同，CDK5是被在神经系统高表达的p35/p25蛋白所激活；因此CDK5在神经系统具有高特异的 …
细胞周期蛋白依赖性激酶5的病理学功能及与运动的关系
2024年11月15日 · 细胞周期蛋白依赖性激酶5（cyclin-dependent kinase 5，CDK5）是一种受脯氨酸诱导的丝氨酸/苏氨酸激酶，在脂肪、大脑、血管、心脏以及骨等多个器官组织中表达。
A decade of CDK5 - Nature Reviews Molecular Cell Biology
2001年10月1日 · Since it was identified a decade ago, cyclin-dependent kinase 5 (CDK5) has emerged as a crucial regulator of neuronal migration in the developing central nervous system.
CDK5: Key Regulator of Apoptosis and Cell Survival - PMC
The atypical cyclin-dependent kinase 5 (CDK5) is considered as a neuron-specific kinase that plays important roles in many cellular functions including cell motility and survival. The …
CDK5: Insights into its roles in diseases - Springer
2025年1月21日 · Cyclin-dependent kinase 5 (CDK5), a unique member of the CDK family, is a proline-directed serine/threonine protein kinase with critical roles in various physiological and …